The Effect of Salpingectomy Operation on Ovarian Reserve

This study aimed to evaluate the effect of salpingectomy operation on ovarian reserve. Ovarian reserve was evaluated by measuring anti-mullerian hormone levels from serum samples taken from the patients before the operation and 6 weeks after the operation. Ovarian doppler flow were evaluated by measuring the ovarian artery pulsatility index with transvaginal ultrasonography preoperatively, postoperative days 2 and postoperative weeks 6 . In our study, it was determined that ovarian functions may be negatively affected in the acute period after salpingectomy operation.

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Key information

Conditions

Ovarian Insufficiency

Age range

37 year–45 year

Sex eligibility

Female

Study type

Observational

Primary location

Dokuz Eylul University School of Medicine

Izmir, 35000, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Women between the ages of 37-45 with continuing menstrual cycles (37 and 45 included)
Patients who will undergo uterine surgery for benign reasons or who will undergo salpingectomy only due to hydrosalpinx, ectopic pregnancy, tubo-ovarian abscess
Patients who have not had ovarian surgery before
Those without menopause and premature ovarian failure
Patients who accept the study

Exclusion criteria

Age younger than 37 or older than 45
Those who want to withdraw from the study
Those who do not come for follow-up examination
Use of drugs that affect ovarian reserve
Any surgical procedure performed on the ovaries during the operation
No menstrual bleeding in the last year
Patients who received radiotherapy and hormonal therapy within 3 months before surgery

Treatment and study plan

bilateral salpingectomy, ovarian arter doppler ultrasonography

Procedure

The effect of salpingectomy operation on ovarian reserve

Primary outcomes

right ovarian arter pı

Time frame: perioperative, postoperative days 2 , postoperative weeks 6

rate of 0,87/ 0,84/ 0,76
left ovarian arter pı

Time frame: perioperative, postoperative days 2, postoperative weeks 6

rate of 0,89/ 0,79/ 0.80
AMH levels

Time frame: perioperative-postoperative weeks 6

Concentration of 1 ng/mL / 0,79 ng/mL

Sponsors and collaborators

Lead sponsor

Dokuz Eylul University

Other

Registry information

Official study title

Evaluation of the Effect of Salpingectomy Operation on Ovarian Reserve With Anti-Mullerian Hormone and Ovarian Doppler Ultrasonography

Important dates

Study start: 2020
Primary completion: 2021
Study completion: 2021
First posted: Mar 31, 2025
Registry last updated: Apr 3, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed