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Completed

NCT Number: NCT07347470

The Effect of Rhythmic Auditory Stimulation on VOR Gain Adaptation Among Healthy Adults - A Randomized Clinical Trial "VOR - Vestibulo-ocular Reflex"

The goal of this study is to learn whether adding rhythmic sound (a metronome beat or music) to eye-head exercises can improve the reflex that keeps vision clear during head movement. This reflex, called the vestibulo-ocular reflex (VOR), helps maintain visual stability during activities such as walking, turning, or bending. This type of training may help people with dizziness or balance problems, but this study focuses on healthy adults.

The main questions addressed are:

Does performing VOR exercises with a steady metronome beat improve the VOR more than performing the same exercises in silence?

Does performing the exercises while listening to self-selected rhythmic music also improve the VOR, and is the effect better or worse than a metronome?

Do the different sound conditions change how difficult the training feels or how dizzy participants feel?

Three conditions will be compared:

Silence: standard VOR training with no sound Metronome: training timed to a simple, steady beat Music: training performed while listening to self-selected music with a clear beat

The study will assess whether adding rhythmic sound leads to greater improvement in VOR gain and whether one type of sound is more effective than another.

Participants are healthy adults. Participants will:

Attend the laboratory for three separate visits, each with a different sound condition (silence, metronome, and music).

Visits will be at least 48 hours apart.

Wear specialized goggles that record eye and head movements (EyeSeeCam).

Perform brief eye-head tests before and after training, consisting of rapid head turns while maintaining fixation on a visual target.

Complete 15 minutes of Incremental VOR adaptation training during each visit, repeating rapid head turns while fixating on a laser projected target (StableEyes). In some sessions movements will be synchronized to a metronome or music.

Rate perceived training difficulty, ease of following the rhythm, and any dizziness or discomfort.

By comparing results across the three conditions within the same participants, the study will determine whether a simple, low-cost rhythmic cue can enhance the effects of standard VOR exercises without increasing discomfort.

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Key information

Conditions

Age range

18 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Sheba Medical Center

Ramat Gan, 5300419, Israel

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy

Exclusion criteria

  • Vestibular disorders. Neurologic conditions, Deafness, Blindness

Treatment and study plan

Rhythmic Auditory Stimulation

Other

the same 15 minutes of vestibular adaptation training will be completed by all participants in 3 different conditions: silence, metronome, and music. participants will be instructed to synchronize their head impulses to the beat in the auditory conditions.

Silence

Other

15 minutes of vestibular adaptation training without any background noise.

Primary outcomes

  1. Change in horizontal semicircular canal VOR gain for active and passive head impulses

    Time frame: Gains values- Baseline (pre-training) and immediately after each training session (post-training). Assessed during each of the three sessions. The sessions are separated by at least 48 hours and all three will be completed over approximately 2 - 4 weeks.

    The change in vestibulo-ocular reflex (VOR) gain for the horizontal semicircular canals, measured using video head impulse testing (vHIT), calculated as the difference between pre-training and post-training gain values for both active and passive head impulses under each auditory condition (Silence, Metronome, and Music).

Secondary outcomes

  1. Self-reported training difficulty and adverse symptoms

    Time frame: Immediately after completion of each of the three training sessions. Sessions will be separated by at least 48 hours and all three will be completed over approximately 2-4 weeks.

    Participant-reported ratings of training difficulty and adverse symptoms (including dizziness and nausea), assessed using 1-10 visual analog scales completed after each training session under each of the three auditory conditions.

Sponsors and collaborators

Lead sponsor

University of Haifa

Other

Registry information

Official study title

Dancing Eyes: The Effect of Rhythmic Auditory Stimulation on VOR Gain Adaptation Among Healthy Adults - A Randomized Clinical Trial

Acronym: VOR

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jan 16, 2026
Registry last updated
May 1, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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