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Completed

NCT Number: NCT07233005

The Effect of Quadriceps Sets Exercise on Knee Joint Biomechanics and Functional Outcomes of Post-Total Knee Arthroplasty Patients

Lower limb strengthening, especially the quadriceps training, is of much necessity for patients with knee arthroplasty. As the quadriceps strengthening exercises play a vital role in controlling gait pattern during walking and different activities. Vastus inetrmedius muscle responsible for the last 10 degree of knee extension. This enable the knee joint to be in locked position which is the stable position during gait.

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Key information

Conditions

Total Knee Arthroplasty

Age range

40 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Jouf University

Sakakah, Saudi Arabia

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age (ranging from 40 to 60 years old).
  • Weight (ranging from 65 to 75 kg).
  • Height (ranging from 150 to 165 cm)
  • Sex ( male/ female).
  • Patients who undergoing total knee arthroplasty after 1 months until one year after operation.

Exclusion criteria

  • Cognitive impairment.
  • Neuromuscular impairment.
  • Patient can't walk alone (need of assistive device).

Treatment and study plan

Quadriceps Set Exercise

Procedure

Quadriceps knee set exercises was introduced with the patient in sitting position and pillow was placed under his knee joint then ask patient to dorsiflex his ankle and extend knee make hold 10 second then relax. Two exercises session per week for four week.

Terminal Knee Extension

Procedure

Terminal knee extension exercise using Thera band was introduced with the patient in sitting or standing position and the theraband was placed around his knee joint. Two exercises session per week for four week.

traditional physical therapy

Procedure

Traditional physical therapy program will include passive stretching exercise to the hamstrings while the patient is supine lying flex the hip while the knee extended and hold for 30-45 seconds, strengthening exercise to the guadriceps muscle by extending the knee whie the patient is in the sitting position.

Primary outcomes

  1. Visual Analoge Scale (VAS)

    Time frame: Four weeks

    VAS is a straight horizontal line of usually 100 mm. The ends are defined as the extreme limits of the pain . It is orientated from the left (worst) to the right (least) pain.

  2. Quadriceps Muscle Strength

    Time frame: 4 weeks

    it will be measured using a hand held dynamometer.

Secondary outcomes

  1. Range of Motion (ROM)

    Time frame: 4 weeks

    ROM of last ten degree of knee extension measured by goniometer

  2. Oxford Knee Score (OKS)

    Time frame: 4 weeks

    The OKS is a patient reported outcome measure that consists of 12 questions about an individual's level of function, activities of daily living and how they have been affected by pain over the preceding four weeks.The Oxford Knee Score (OKS) ranges from 0 to 48, 0 = Worst possible knee pain/function. 48 = Best possible knee pain/function.

  3. The Western Ontario and McMaster Universities Osteoarthritis Index (The WOMAC)

    Time frame: 4 weeks

    It is a questionnaire of 24-item. Self-administered tool used to assess pain, stiffness, and physical function in patients with hip and knee osteoarthritis.

    WOMAC Likert Version (0-96 total)

    Each item scored:

    0 = none

    • = mild
    • = moderate
    • = severe
    • = extreme Total score ranges from: 0 = best possible (no symptoms). 96 = worst possible (severe symptoms).

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Nov 18, 2025
Registry last updated
Mar 10, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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