The Effect of Prebiotic B-GOS on the Immune Function, Metabolism and Gut Microbiota of Elderly People

Inclusion criteria

• Aged between 65 and 80 years of age.
• In good general health
• The volunteer has given written informed consent to participate and is willing to participate in the entire study.

Exclusion criteria

• History or evidence of disease of the gastrointestinal tract; such as tumour, irritable bowel syndrome, etc., within the previous 5 years.
• Family history of colorectal cancer in under 50's
• Consumed probiotic or prebiotic preparations on a regular basis (at least 3 times per week) in the last 2 weeks.
• Former participation in another study involving prebiotic or probiotic preparations or investigational drugs within the previous 6 months, or intention to use such drugs during the course of the study (please note sensory evaluations are still permitted).
• Undergone surgical resection of any part of the bowel.
• History of malignancy within the previous 5 years (with exception of well-treated basal cell carcinoma or in situ cervical carcinoma).
• Smoker
• Lactose intolerant
• Allergic to gluten
• Currently prescribed immunosuppressive drugs. Participants will be required to withdraw should they begin taking any of the ineligible medication.
• Intention to use regularly other medication which affects gastrointestinal motility and/or perception.
• History of alcohol or drug misuse.
• Suffer from any major conditions involving the following:

Head, Ears, Eyes, Nose and Throat Dermatological/Connective tissue Coeliac disease Neurological Lymphatic Urogenital/Rectal Gastroenterological Abdominal Respiratory Cardiovascular Incontinence