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Completed

NCT Number: NCT06485531

The Effect of Pranayama on Pain and Respiration After Coronary Bypass Surgery

After CABG surgery, patients tend to breathe superficially because they experience pain while breathing. By restricting deep inspiration and cough; There is a decrease in lung tidal volume, vital capacity, and functional residual capacity. Accordingly, alveolar ventilation also decreases, and the oxygenation levels of the organs decrease due to alveolar collapse or developing hypoxemia. Due to the pain experienced, patients cannot cough and secretions accumulate in the alveoli. Due to accumulated secretions, patients are more prone to atelectasis and lung infections. The risk of pulmonary embolism increases in patients due to the limitation of movement caused by pain. It is aimed to replace these weak breathing patterns with conscious breathing patterns provided by pranayama. While pranayama improves regular, slow, and deep breathing, it activates nasal breathing and provides diaphragmatic breathing. Thanks to the suction pressure created in the chest cavity with diaphragmatic breathing, the venous return of blood also improves. Along with all these changes, it also helps reduce the heart's workload by regulating circulatory functions such as blood pressure, heart rate, left ventricular pressure, and coronary artery diameter. Alternating nasal breathing, slow and deep breathing, applied during pranayama, helps relieve breathing work in eliminating excessive breathing patterns. In addition, nasal breathing balances sympathetic and parasympathetic activity and makes an important contribution to the regulation of the activities of the autonomic nervous system. The vagus nerve, which has a parasympathetic effect, stimulates the left nostril, diagram, stomach, hypothalamus, pineal gland, and suprachiasmatic nucleus and stimulates the diaphragm and stomach, and with this control of the autonomic nervous system, it helps to keep the respiratory rate within normal ranges, improve breathing, reduce stress hormones and help relaxation. Controlled inspiration, breath holding, and slow expiration practices performed with pranayama also contribute to increasing the general capacity of the lungs and gradually improving respiratory functions.

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Key information

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Tuğba Albayram

Gaziantep, Şehitkamil, 27310, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • CABG surgery performed on a stopped heart (On pump),
  • Cardiopulmonary risk index score ≤2
  • Those aged 18 and over,
  • Being literate and communicative,
  • American Society of Anesthesiologists (ASA) classification I or II,
  • Preoperative respiratory function tests with normal FEV1, FVC, FEV1/FVC values,
  • No complications developed during and after the surgical intervention,
  • An analgesic drug with the same active ingredient is applied to control pain after surgical intervention,
  • Patients who were administered antibiotics with the same active ingredient after surgical intervention were included.

Exclusion criteria

  • CABG surgery performed on a working heart (off-pump),
  • Cardiopulmonary risk index score ≥4
  • Complications developing during or after surgery,
  • Intubated,
  • Those with chronic pain in the pre-surgical period,
  • Those with limited movement activity before surgery,
  • Having a body mass index (BMI≥30),
  • Patients who could not adapt to and tolerate the pranayama technique were not included in the study.

Treatment and study plan

Pranamaya

Other

Pranamaya

Pursed Lips Breathing

Other

Pursed Lips Breathing

Primary outcomes

  1. postoperative FVC

    Time frame: From admission to discharge, up to 1 week

    Improvement in FVC in patients treated with Pranayama after CABG

  2. FEV1

    Time frame: From admission to discharge, up to 1 week

    Improvement in FEV1 in patients treated with Pranayama after CABG

  3. FEV1/FVC level

    Time frame: From admission to discharge, up to 1 week

    Improvement in FEV1/FVC level in patients treated with Pranayama after CABG

  4. Change in postoperative pain measured by VAS

    Time frame: From surgery to 3 days after surgery

    Change in postoperative pain measured by VAS in patients who underwent pranayama after CABG

Sponsors and collaborators

Lead sponsor

Istanbul University - Cerrahpasa

Other

Registry information

Official study title

The Effect of Pranayama and Pursed Lip Breathing Exercise on Pain and Respiration After Coronary Bypass Surgery

Important dates

Study start
2022
Primary completion
2023
Study completion
2023
First posted
Jul 3, 2024
Registry last updated
Jul 3, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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