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NCT Number: NCT07491549

The Effect of Pain Education Group Therapy and Its Impact on Chronic Pain, Kinesiophobia, and Physical Activity

The goal of this clinical trial is to learn if pain knowledge group intervention among chronic pain patients would influence their level of physical activity, pain intensity, depression, kinesiophobia and central sensitization. The main question it aims to answer is:

Primary hypothesis: pain education will decrease participants' depression and pain intensity and increase their physical activity.

There is no comparison group.

Participants will participate in a 6-week pain knowledge intervention where they will be learning about sleep, stress models, physical activity benefits, pain neurobiology, mindfulness, pain medication.

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Key information

Conditions

Chronic Pain Anxiety Disorders Behavior Behavioral Symptoms Depression Kinesiophobia Mental Disorders Motor Activity Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Phobic Disorders Signs and Symptoms

Age range

16 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Tartu University Hospital

Tartu, 50406, Estonia

Location status: Recruiting

Location contact

Hanna Kalajas-Tilga, PhD

CONTACT

[email protected]

372 58361041

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Pain lasting longer than 3 months,
  • Consequences resulting from long-term pain (such as decreased physical activity, sleep disturbances, fatigue, low mood, etc.)

Exclusion criteria

  • Surgery that occurred less than 3 months prior
  • Fracture or limb trauma that occurred less than 3 months prior

Treatment and study plan

Pain education

Behavioral

In one group there will be 8-12 participants who will meet once a week during 6 -weeks time. The educational sessions will be 2-hours long including sometimes some exercises and also reflection of the participants.

Other names: pain neuroscience education, pain management education

Primary outcomes

  1. Change of pain intensity from baseline to 6-weeks

    Time frame: from enrollment to the end of treatment at 6 weeks

    Pain is measured using Graded Chronic Pain Scale -Revised where the lowest value is 0 and the highest is 100. The higher the score, the more pain the subject feels.

  2. Change of pain intensity from baseline to 6-weeks

    Time frame: from enrollment to the end of treatment at 6 weeks

    Pain is measured using Brief Pain Inventory Short form where the lowest value is 0 and the highest value is 10. The higher the score, the more pain the subject feels.

Secondary outcomes

  1. Change in depression from baseline to 6-weeks

    Time frame: from enrollment to the end of treatment at 6 weeks

    Depression is measured using Emotional well-being questionnaire where the lowest value is 0 and the highest value is 100. Lower score indicates worse health condition.

Study contacts

Contact information is provided by the study sponsor or research team.

Hanna Kalajas-Tilga, PhD

CONTACT

[email protected]

+372 5816 1041

Mati Arendi, PhD

CONTACT

Sponsors and collaborators

Lead sponsor

University of Tartu

Other

Registry information

Official study title

Physical Activity in Patients With Chronic Pain, Its Adherence to WHO Physical Activity Recommendations, and Its Associations With Kinesiophobia, Central Sensitization, Depression, and Pain Intensity

Important dates

Study start
2026
Primary completion
2030
Study completion
2030
First posted
Mar 24, 2026
Registry last updated
Mar 30, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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