Skip to main content
OpenTrials
Completed

NCT Number: NCT01342614

The Effect of Metformin on the Correlation Between Hyperinsulinemia and Hypertension

The objective of this study is to investigate the effect of metformin on the correlation between hyperinsulinemia and hypertension.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Diabetes Mellitus Cardiovascular Diseases Endocrine System Diseases Essential Hypertension Glucose Metabolism Disorders Hyperinsulinism Hypertension Insulin Resistance Metabolic Diseases Nutritional and Metabolic Diseases Vascular Diseases

Age range

20 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 20 to 65 years of age, regardless of sex
  • duration of hypertension was <5 years
  • overweight or obesity, mild to moderate hypertension, receive no euglycemic agent or antiobesity drug

Treatment and study plan

Fosinopril

Drug

Fosinopril group received fosinopril, 10mg, once per day.

metformin

Drug

Metformin group was treated with metformin hydrochloride, 500mg, three times per day

Primary outcomes

  1. Blood pressure measurement

    Time frame: 8 weeks

Sponsors and collaborators

Lead sponsor

China-Japan Friendship Hospital

Other

Registry information

Important dates

Study start
2006
Primary completion
2009
Study completion
2009
First posted
Apr 27, 2011
Registry last updated
May 13, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.