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NCT Number: NCT03741413

The Effect of Message Framing on Blood Donation-Study 1

Rh negative blood group is a rare blood group in China, as it only accounts for 0.3-0.4 percent of the Han population. Therefore, low inventory is often found in blood collection and supply agencies in many regions in China. On July 18, 2018 blood stockpile of O-negative and B-negative in Guangzhou Blood Center reached the warning line, and we took measures for emergency recruitment. O-negative and B-negative blood donors whose last donation dates were between January 1, 2015 and December 31, 2017 were identified and randomly assigned to three groups. Three different recruitment text messages were send to these groups respectively. At the same time, A-negative and AB-negative blood donors were marked as control group. We observed the re-donation rates among four groups within three months.

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Key information

Conditions

Rh Negative Blood Donor

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Guangzhou Blood Center

Guangzhou, Guangdong, 510095, China

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Rh- negative blood donors whose last donations were between January 1, 2015 and December 31, 2017.

Exclusion criteria

  • Donors with an obviously invalid phone number. Donors whose serological results of the last donation were positive.

Treatment and study plan

Gain-frame SMS

Other

Emergency recruitment cell phone short messages that emphasizing donating blood can save patients' lives were sent to donors in this group.

Loss-frame SMS

Other

Emergency recruitment cell phone short messages emphasizing that donating blood can prevent patients from death were sent to donors in this group.

Control SMS

Other

Emergency recruitment cell phone short messages that only mentioning the low Rh-negative blood stockpile were sent to donors in this group.

Primary outcomes

  1. Re-donation rate

    Time frame: 3 months

    Intention-to-treat were applied. Re-donation rate was defined as the number of donors in each group devided by donors who re-donated within 3 months.

Sponsors and collaborators

Lead sponsor

Guangzhou Blood Center

Other Gov

Registry information

Official study title

Saving a Life or Preventing a Death: the Effect of Message Framing on Blood Donation Among Rh Negative Donors

Important dates

Study start
2018
Primary completion
2018
Study completion
2018
First posted
Nov 14, 2018
Registry last updated
May 5, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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