The Effect of LymphaTouch® and Manual Lymphatic Drainage on Extremity Circumference Measurements in Lymphedema

This retrospective study will be conducted using the medical records of lymphedema patients followed in the Physical Medicine and Rehabilitation outpatient clinics and lymphedema unit of Istanbul Physical Medicine and Rehabilitation Training and Research Hospital. Women and men aged 18-75 years with a diagnosis of upper or lower extremity lymphedema will be included. Sociodemographic and clinical data of the patients will be recorded, and participants will be divided into two treatment groups: those who received LymphaTouch® therapy and those who underwent Manual Lymphatic Drainage (MLD). Pre- and post-treatment extremity circumference measurements will be obtained from patient records, and the differences between the groups will be compared.

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Key information

Conditions

Lymphedema Hemic and Lymphatic Diseases Lymphatic Diseases

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Istanbul Physical Medicine Rehabilitation Training and Research Hospital

Istanbul, Turkey (Türkiye)

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Clinically diagnosed with lymphedema
Aged between 18 and 75 years
Complete pre- and post-treatment extremity circumference measurements available in patient records

Exclusion criteria

History of systemic diseases such as diabetes, rheumatologic disorders, or malignancy
Presence of neurological disorders (e.g., polyneuropathy, multiple sclerosis, history of stroke)
Pregnancy
History of surgery or major trauma involving the affected limb within the past 6 months
History of injection therapy or physical therapy applied to the same limb within the past 6 months
History of infection or active dermatological disease affecting the limb
Incomplete or inconsistent data in patient records

Treatment and study plan

No intervention

Other

No intervention

Primary outcomes

Change in Extremity Circumference (cm):

Time frame: Baseline

he primary outcome will be the difference in limb circumference measurements before and after treatment. Circumference values will be obtained from standardized anatomical landmarks, including the wrist/ankle, and at 10 cm, 20 cm, 30 cm, and 40 cm proximal to the metatarsophalangeal (MTP) or metacarpophalangeal (MCP) joint. A greater reduction in circumference indicates a more effective treatment response.

Sponsors and collaborators

Lead sponsor

Istanbul Physical Medicine Rehabilitation Training and Research Hospital

Other Gov

Registry information

Official study title

The Effect of LymphaTouch® and Manual Lymphatic Drainage on Extremity Circumference Measurements in Lymphedema: A Retrospective Study

Important dates

Study start: 2025
Primary completion: 2025
Study completion: 2025
First posted: Nov 20, 2025
Registry last updated: Nov 20, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed