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Completed

NCT Number: NCT00615277

The Effect of Long-Chain Polyunsaturated Fatty Acids on Cognitive Performance and Mood

The study investigates whether dietary intake of omega-3 long-chain polyunsaturated fatty acids affects learning and mood of healthy young adults.

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Key information

Conditions

Healthy

Age range

16 year–24 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

The long-chain polyunsaturated fatty acids (LCPUFA) EPA (eicosapentaenoic acid), DHA (docosahexaenoic acid) of the omega-3 series and AA (arachidonic acid) of the omega-6 series are building blocks of all cell membranes and are found in high concentrations in retina and brain. Food sources of LA and ALA are vegetable oils, nuts and seeds. Since low conversion rates from ALA to DHA are a characteristic of human metabolism, adequate dietary provision with the long-chained omega-3 molecules depends primarily on individual eating habits. While AA is abundant in meat and dairy products, EPA and DHA are found in noteworthy concentrations only in certain species of fatty fish, such as salmon or mackerel.

The study investigates whether participants receiving an omega-3 supplement over a period of 4 month, perform better on a series of cognitive tests, than the participants allocated to the placebo group.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy young adults

Exclusion criteria

  • Coagulation disorder

Treatment and study plan

Omega-3 fatty acids

Dietary Supplement

600 mg EPA 120mg DHA daily, 16 weeks

Primary outcomes

  1. Cognition

    Time frame: Before intervention and after 16 weeks of intervention

Secondary outcomes

  1. Mood

    Time frame: Before intervention and after 16 weeks of intervention

Sponsors and collaborators

Lead sponsor

University of Ulm

Other

Collaborators

  • Cognitive Drug Research Ltd
  • Philipps University Marburg

Registry information

Official study title

The Effect of Long-Chain Polyunsaturated Fatty Acids on Cognitive Performance and Mood of Healthy Young Adults

Important dates

Study start
2006
Primary completion
2007
First posted
Feb 14, 2008
Registry last updated
Feb 14, 2008

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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