Skip to main content
OpenTrials
Completed

NCT Number: NCT07629713

The Effect of Local Anesthesia on Postopanalgesia in Patients Using Head Holder

Aim:The head holder used in neurosurgery operations causes pain in patients both peroperatively and postoperatively.Severe pain-related hemodynamic changes are seen in these participants.In our study, the investigators compared the effects of two different concentrations of lidocaine on the perioperative and postoperative hemodynamic response caused by the application of the head-holder, and the pain observed in the postoperative period.

Method: Ethics committee approval and participants consent were obtained. Lidocaine 0.5% in Group 1 and 1% lidocaine in Group 2 was administered subcutaneously, 3 ml to each three points, in a total of 9 ml. Postoperative analgesic efficacy and tramadol consumption amounts of different concentrations of lidocaine were compared in participants who used a head holder.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Postoperative Pain, Acute Brain Diseases Brain Neoplasms Central Nervous System Diseases Central Nervous System Neoplasms Endocrine Gland Neoplasms Endocrine System Diseases Hypothalamic Diseases Hypothalamic Neoplasms Neoplasms Neoplasms by Site Nervous System Diseases Nervous System Neoplasms Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Pituitary Diseases Pituitary Neoplasms Postoperative Complications Signs and Symptoms Supratentorial Neoplasms

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Kocaeli Üniversitesi Tıp Fakültesi Hastanesi

Kocaeli, İzmit, 41100, Turkey (Türkiye)

About this study

1% concentration of lidocaine as skin infiltration before wearing a head-holder.

compared to 0.5% concentration lidocaine application, pain was controlled in the first hour of the postoperative period.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • ASA 2-3

Exclusion criteria

  • ASA 4,
  • going to the intensive care unit in the postoperative period

Treatment and study plan

lidocaine was administered subcutaneously at 0.5% concentration.

Drug

In Group 1, lidocaine was administered subcutaneously at 0.5% concentration.

Other names: aritmal

lidocaine was administered subcutaneously at 1% concentration.

Drug

In Group 2, lidocaine was administered subcutaneously at 1% concentration.

Other names: aritmal

Primary outcomes

  1. The aim of this study is to compare postoperative pain levels between two groups of neurosurgery patients who underwent surgery using a head holder.

    Time frame: 5 years

    The aim is to alter pain levels of these two operated groups at the first, third, sixth, twelfth, and twenty-fourth hours after surgery. Change from baseline in pain Scores on the Visiual Analog Scale at one day after surgery

Sponsors and collaborators

Lead sponsor

Kocaeli University

Other

Registry information

Official study title

The Effect of Lidocaine Injection at Different Concentrations on Postoperative Pain in Patients Using Head Holder.

Important dates

Study start
2018
Primary completion
2019
Study completion
2020
First posted
Jun 5, 2026
Registry last updated
Jun 5, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.