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NCT Number: NCT07002307

The Effect of Honey-sweetened Coffee, Black Tea and Green Tea on Some Physiological Parameters

The goal of this clinical trial is to investigate whether a three-day consumption of honey-sweetened black tea, green tea, and coffee will have an effect on blood pressure, heart rate, and blood glucose. The main questions it aims to answer are:

Does honey-sweetened black tea, green tea, and coffee, respectively, have the ability to influence blood pressure, heart rate, or blood glucose level?

Research will compare honey-sweetened black tea, green tea, and coffee to a placebo (warm water) to see if honey-sweetened black tea, green tea, and coffee work to reduce or increase blood pressure, heart rate, or blood glucose.

Participants will:

Take honey-sweetened black tea, green tea, and coffee, OR plain black tea, green tea, and coffee, OR warm water, one cup a day for 3 days The beverages will be taken at the Physiology laboratory, University of Uyo, and the participants will be observed for 60 minutes, during which their blood pressure, heart rate, and blood glucose level will be measured. This procedure will be repeated for the 3 days of study.

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Key information

Conditions

Blood Pressure Blood Glucose Heart Rate

Age range

18 year–26 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Physiology laboratory, Physiology Department, Faculty of Basic Medical Sciences, University of Uyo

Uyo, Akwa Ibom State, 520003, Nigeria

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Inclusion criteria

are as follows:

  • Age between 18 and 26
  • Non-habitual coffee and tea drinkers who consume coffee, green tea, or black tea 2-5 times in the last two months
  • Non-allergic to coffee, green tea, black tea, or honey
  • Absence of medication use
  • Will refrain from ingesting energy drinks, carbonated beverages, caffeinated beverages, or food for 24 hours before the study and throughout the study periods
  • Will not consume anything except water after 11 p.m. during the experimental days Will be available and cooperate throughout the study duration.

Exclusion criteria

Exclusion criteria

are as follows:

  • Presence of cardiovascular disorders, hypertension, or diabetes
  • Blood pressure above 120/80 mmHg and random blood glucose above 125 mg/dL
  • Alcohol intake
  • Smoking
  • Habitual coffee or tea drinker

Treatment and study plan

Warm water at 35 oC

Other

The placebo for the control group

Coffee

Other

Instant coffee, Nescafé Gold Blend, manufactured by Nestlé Coffee Brand, Nestlé Global

Honey-sweetened coffee

Other

Instant coffee plus raw dark amber honey produced by Apis mellifera adansonii

Green Tea

Other

Qualitea Natural Green Tea, packed by Qualitea Ceylon (PVT) LTD

Honey-sweetened green tea

Other

Green tea plus honey

Black tea

Other

Lipton Yellow Label Black Tea

Honey-sweetened black tea

Other

Black tea plus honey

Primary outcomes

  1. Blood pressure

    Time frame: Will be measured before consumption of the beverages and at 15, 30, 45, and 60 minutes after consumption of the beverages. This procedure will be repeated for 3 consecutive days.

  2. Heart rate

    Time frame: Will be measured before consumption of the beverages and at 15, 30, 45, and 60 minutes after consumption of the beverages. This procedure will be repeated for 3 consecutive days.

  3. Blood glucose

    Time frame: Will be measured before consumption of the beverages and at 30 and 60 minutes after consumption of the beverages. This procedure will be repeated for 3 consecutive days.

Secondary outcomes

  1. Age

    Time frame: Will obtained during the eligibility process

  2. Height

    Time frame: Will be measured on the first day of the experiment before the commencement of the experiment.

  3. Body weight

    Time frame: Measurements will be taken over the course of the 3-day study prior to the commencement of the experiment each day.

Sponsors and collaborators

Lead sponsor

University of Uyo Teaching Hospital

Other

Registry information

Official study title

The Effect of Honey-sweetened Coffee, Black Tea and Green Tea on Blood Pressure, Heart Rate and Blood Glucose

Important dates

Study start
2023
Primary completion
2023
Study completion
2023
First posted
Jun 3, 2025
Registry last updated
Jun 15, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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