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OpenTrials
Completed

NCT Number: NCT06099483

The Effect of Exercise on Brain Functions

Concept of action simulation; It is an internal representation of motor programs that does not involve explicit movement. Motor imagery method (MI) or movement observation (HG) method are considered two separate action simulation methods that activate motor regions in the brain. Both methods remain a popular and effective tool for improving motor learning. Research has shown that clinicians working in rehabilitation settings are aware of the needs of patients, athletes, etc. are recommended as methods that participants can use to improve their motor skills.

Motor imagery training is a dynamic mental process in which a movement is mentally visualized without any visible movement or any voluntary motor muscle activation. Movement observation training is a method that involves internal, real-time motor simulation of movements in which the observer visually perceives movements performed by another. Mirror neurons, located primarily in the rostral part of the inferior parietal lobe and the ventral premotor cortex, are activated both when an action is physically performed and when the action is observed being performed by another person. Studies using neuroimaging techniques have provided support for this theory by showing that many areas known to be active during action simulation, such as the dorsal pre-motor cortex, supplementary motor area, superior parietal lobe, and intraparietal sulcus, are indeed active during both HG and MI. There is evidence in the literature that MI and HG also trigger sympathetic nervous system activation. There may be changes in respiration, heart rate and skin temperature, as well as an increase in electrodermal activity.

EEG is an inexpensive, noninvasive, and simple examination that can be used to evaluate neurophysiological functions by measuring electrical activity. Understanding the mechanism of beta rhythms is important because they are associated with conscious thinking, logical thinking, memory and problem solving, whereas suppression of beta waves contributes to depression and cognitive decline.

This study will investigate the effectiveness of exercising or watching or imagining exercise on brain functions.

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Key information

Conditions

Age range

18 year–55 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Ebrar Atak

Yalova, 77100, Turkey (Türkiye)

About this study

Participants in the study were divided into 3 groups. One group was shown breathing exercises and asked to imagine these exercises(Motor imagery and action observatin). The second group was made to do active exercises(The same exercises used in motor imagery and action observation were actively performed). The third group was not made to do anything. The exercises lasted 10 minutes. Watching and imagining the movement was also organized as a 10-minute program. That's why the control group was not allowed to do anything for 10 minutes. EEG recordings were taken during this 10-minute period in all three groups.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Volunteering to participate in the study
  • Being between the ages of 18-40
  • Not using an assistive device
  • Having been using the same medications for the last 4 weeks
  • No additional comorbid diseases of the orthopedic, neurological or cardiac system
  • Getting 30 or more points from each of the Kinesthetic and Visual Imagination Questionnaire -20 (KGIA-20) visual imagination score and kinesthetic imagination score (The purpose of this criterion is to check that the patients who will be distributed to the cognitive rehabilitation group have sufficient imagination ability and to be able to do the exercises.)

Exclusion criteria

  • Not agreeing to participate in the study
  • Patients who have used oral corticosteroid drugs in the last 4 weeks
  • Participants who cannot understand verbal instructions and are visually impaired
  • Have currently participated in another clinical trial within the last 30 days that may affect the results of the study

Treatment and study plan

Action observation and motor imagery

Other

EEG recording was taken while watching a 10-minute video recording of specified breathing exercises and imagining the exercises.

Active breathing exercise

Other

EEG recording was taken while the physiotherapist performed active breathing exercises for 10 minutes.

Control Group

Other

EEG recording was taken while resting with eyes closed for 10 minutes.

Primary outcomes

  1. Acute effect on brain electrical activity

    Time frame: up to 24 weeks

    Motor imagery exercise combined with action observation has an acute effect on brain electrical activity in healthy sedentary individuals.

Secondary outcomes

  1. Acute effect on cardioventilatory responses

    Time frame: up to 24 weeks

    Motor imagery exercise combined with action observation has an acute effect on cardioventilatory responses in healthy sedentary individuals.

Sponsors and collaborators

Lead sponsor

Istanbul Medipol University Hospital

Other

Collaborators

  • Istanbul Gedik University

Registry information

Official study title

Acute Effect of Motor Imagery Exercise Combined With Movement Observation on Brain Electrical Activity and Cardioventilatory Responses in Healthy Sedentary Individuals.

Important dates

Study start
2023
Primary completion
2023
Study completion
2023
First posted
Oct 25, 2023
Registry last updated
Mar 22, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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