Skip to main content
OpenTrials
Completed

NCT Number: NCT02936336

The Effect of Exercise Intervention on the Community's Older Adults

Osteoporosis is a serious global health problem, second only to cardiovascular disease. Osteoporosis is the most common metabolic bone disease in the elderly population, characterized by loss of bone mineral density (BMD) and continuous destruction of bone microstructure, especially in postmenopausal women. It gives rise to bone fragility and fracture risk. Moreover, as people grow older, falls frequently occur with high severity, and nearly 35% to 45% of persons aged 65 or older fall at least once a year. Osteoporotic fractures increase mortality, morbidity, chronic pain, and the cost of social care and it decreases the quality of life. Here, investigators plan to perform different exercise interventions such as circuit exercise, aerobic dance and Tai Chi on the community's older adults to evaluate whether exercise intervention could improve the bone mineral density, physical fitness, muscle strength or quality of life.

Completed

Looking for future studies?

Notify Me

Key information

Age range

45 year–85 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Sports Medicine Center, Chang Gung Memorial Hospital

Pizi, 613, Taiwan

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Being >45 years-of-age,
  • Healthy and physically independent.

Exclusion criteria

  • The exclusion criteria were individuals on hormone replacement therapy and those with cognitive impairment, progressive debilitating conditions, bone fractures, or any medical contraindications to administering the fitness assessment.

Treatment and study plan

Exercise

Other

circuit exercise, aerobic dance and Tai Chi exercise

Primary outcomes

  1. Change from baseline bone mineral density

    Time frame: Pre-intervention, 3-month, 6-month, 9-month-follow-up

    Bone mineral density measurement is measured by dual-energy x-ray absorptiometry (DXA). Measurements are made over the lumbar spine and over the upper part of the hip and the measurement is assessed at Pre-intervention, 3-month, 6-month, 9-month-follow-up.

Secondary outcomes

  1. Change from baseline elbow muscle strength

    Time frame: Pre-intervention, 3-month, 6-month, 9-month-follow-up

    Extension and flexion of elbow were tested by the HUMAC NORM system (CSMi, Stoughton, MA) with the eccentric/concentric contraction mode at an angular velocity of 60 degrees/s.Isokinetic tests were performed five times for each participant, and each test was separated by a rest period of 3 min.The Muscle strength was present as a peak torque which was normalized to body weight (Unit:Nm/kg). The participants are assessed at Pre-intervention, 3-month, 6-month, 9-month-follow-up.

  2. Change from baseline shoulder muscle strength

    Time frame: Pre-intervention, 3-month, 6-month, 9-month-follow-up

    Extension and flexion of shoulder were tested by the HUMAC NORM system (CSMi, Stoughton, MA) with the eccentric/concentric contraction mode at an angular velocity of 60 degrees/s.Isokinetic tests were performed five times for each participant, and each test was separated by a rest period of 3 min.The Muscle strength was present as a peak torque which was normalized to body weight (Unit:Nm/kg). The participants are assessed at Pre-intervention, 3-month, 6-month, 9-month-follow-up.

  3. Change from baseline hip muscle strength

    Time frame: Pre-intervention, 3-month, 6-month, 9-month-follow-up

    Extension and flexion of hip were tested by the HUMAC NORM system (CSMi, Stoughton, MA) with the eccentric/concentric contraction mode at an angular velocity of 60 degrees/s.Isokinetic tests were performed five times for each participant, and each test was separated by a rest period of 3 min.The Muscle strength was present as a peak torque which was normalized to body weight (Unit:Nm/kg). The participants are assessed at Pre-intervention, 3-month, 6-month, 9-month-follow-up.

  4. Change from baseline knee muscle strength

    Time frame: Pre-intervention, 3-month, 6-month, 9-month-follow-up

    Extension and flexion of knee were tested by the HUMAC NORM system (CSMi, Stoughton, MA) with the eccentric/concentric contraction mode at an angular velocity of 60 degrees/s.Isokinetic tests were performed five times for each participant, and each test was separated by a rest period of 3 min.The Muscle strength was present as a peak torque which was normalized to body weight (Unit:Nm/kg). The participants are assessed at Pre-intervention, 3-month, 6-month, 9-month-follow-up.

  5. Change from baseline SF-36 questionnaire assessment

    Time frame: Pre-intervention, 3-month, 6-month, 9-month-follow-up

    SF-36 consists of eight scaled scores, which are the weighted sums of the questions in their section. Each scale is directly transformed into a 0-100 scale on the assumption that each question carries equal weight. The lower score the more disability. The higher the score the less disability. Eight sections including physical function, role limitation due to physical problems, bodily pain, general health, vitality, social functioning, role limitation due to emotional problems, and mental health. Additionally, the eight health domains can be used to provide a physical component summary and mental component summary score. The outcome measurement is assessed at Pre-intervention, 3-month, 6-month, 9-month-follow-up.

  6. High-density lipoprotein from blood sample

    Time frame: Pre-intervention, 3-month, 6-month, 9-month-follow-up

    High-density lipoprotein are measured at Pre-intervention, 3-month, 6-month, 9-month-follow-up.

  7. Triglyceride from blood sample

    Time frame: Pre-intervention, 3-month, 6-month, 9-month-follow-up

    Triglyceride are measured at Pre-intervention, 3-month, 6-month, 9-month-follow-up.

  8. Fasting blood glucose from blood sample

    Time frame: Pre-intervention, 3-month, 6-month, 9-month-follow-up

    Fasting blood glucose are measured at Pre-intervention, 3-month, 6-month, 9-month-follow-up.

  9. Blood pressure

    Time frame: Pre-intervention, 3-month, 6-month, 9-month-follow-up

    Diastolic and systolic blood pressure are measured at Pre-intervention, 3-month, 6-month, 9-month-follow-up.

  10. Weight parameters of the subjects

    Time frame: Pre-intervention, 3-month, 6-month, 9-month-follow-up

    Weight (kg) are measured at Pre-intervention, 3-month, 6-month, 9-month-follow-up.

  11. Height parameters of the subjects

    Time frame: Pre-intervention, 3-month, 6-month, 9-month-follow-up

    Height (cm) are measured at Pre-intervention, 3-month, 6-month, 9-month-follow-up.

  12. Waistline parameters of the subjects

    Time frame: Pre-intervention, 3-month, 6-month, 9-month-follow-up

    Waistline (cm) are measured at Pre-intervention, 3-month, 6-month, 9-month-follow-up.

Sponsors and collaborators

Lead sponsor

Chang Gung Memorial Hospital

Other

Registry information

Official study title

The Effect of Exercise Intervention on the Physical Fitness, Bone Mineral Density and Health-related Quality of Life in the Community's Older Adults

Important dates

Study start
2009
Primary completion
2013
Study completion
2013
First posted
Oct 18, 2016
Registry last updated
May 14, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.