Skip to main content
OpenTrials
Completed

NCT Number: NCT04321642

The Effect of Entonox on Stages of Labor in Nulliparous Women

This Trial study about The effect of Entonox associated with duration of labor in Active phase and efficacy for relief pain of labor .So investigators start to study up to 14 months

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Entonox Duration of Labor Nulliparous

Age range

18 year and older

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Rajavithi Hospital

Bangkok, 10400, Thailand

About this study

Investigators will enroll participants in 2 groups by randomized . First group will inhale Entonox and the second group not receive any gas . The participants in Entonox group will inhale gas in 4-5 times for each uterine contraction and Nurse will measure blood pressure , O2 saturation ,pain score before use gas . The outcome,investigators study about Apgar score , duration of labor , pain relief in both group,route of delivery and estimated blood loss

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Nulliparity
  • Age 18 years old or more
  • Gestational age 37-40+6 wks
  • Singleton
  • Cephalic presentation
  • Cervical dilatation > 5 cm
  • Estimated fetal weight 2,500-4,000 gm

Exclusion criteria

  • Estimated fetal weight more than 4,000 gm
  • High risk pregnancy (Hypertension in pregnancy ,Endocrine disorder , autoimmune disorder , epilsepsy etc)
  • SpO2 < 95 %
  • Contraindication for Entonox usage ( Severe head injury , asthma , Pulmonary disease,Otitis media )
  • Drug allergy : Metoclopramide , Dimenhydrinate , Pethidine ,Entonox

Treatment and study plan

Entonox

Drug

Entonox gas with mouth piece

Other names: Entonox gas

Not receive Entonox

Drug

Not receive any gas

Primary outcomes

  1. Effect of Entonox for duration of labor

    Time frame: up to 14 months

    Study about duration of labor after receive Entonox in active phase of labor

Secondary outcomes

  1. Rate of patients who inhaled Entonox for pain relieve

    Time frame: up to 14 months

    % of patients relieve pain after inhaled Entonox , Investigators measure by visual analogue scale

Sponsors and collaborators

Lead sponsor

Department of Medical Services Ministry of Public Health of Thailand

Other Gov

Registry information

Official study title

The Effect of Entonox on Stages of Labor in Nulliparous Women :a Randomized Controlled Trial

Important dates

Study start
2019
Primary completion
2019
Study completion
2020
First posted
Mar 25, 2020
Registry last updated
Dec 3, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.