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OpenTrials
Completed

NCT Number: NCT01584960

The Effect of Endurance Training in Patients With Prostate Cancer

The aim of the present study is to investigate the effect of endurance on PSA doubling time in prostate cancer patients with an elevation in PSA following radical prostatectomy for localized cancer. Furthermore, underlying mechanisms such as reduction in inflammatory markers and improvement in insulin sensitivity and body composition are investigated.

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Key information

Conditions

Prostate Cancer Body Composition, Beneficial Genital Diseases Genital Diseases, Male Genital Neoplasms, Male Glucocorticoid Receptor Deficiency Glucose Metabolism Disorders Hyperinsulinism Insulin Resistance Insulin Sensitivity Male Urogenital Diseases Metabolic Diseases Neoplasms Neoplasms by Site Nutritional and Metabolic Diseases Prostatic Diseases Prostatic Neoplasms Urogenital Diseases Urogenital Neoplasms

Age range

18 year and older

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Centre of Inflammation and Metabolism, Rigshospitalet

Copenhagen, 2100, Denmark

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Prostate cancer patients with an increase in PSA following radical prostatectomy

Exclusion criteria

  • severe cardiovascular disease
  • severe arthritis
  • severe neuropathy
  • severe hypertension
  • therapy with antidiabetic agents
  • other treatment for prostate cancer than radical prostatectomy

Treatment and study plan

Endurance training

Behavioral

2 years of home-based endurance training

Primary outcomes

  1. PSA doubling time

    Time frame: 2 years

Secondary outcomes

  1. Insulin sensitivity, body composition and inflammation status

    Time frame: 0 months, 6 months and 24 months of training

Sponsors and collaborators

Lead sponsor

Inge Holm

Other

Collaborators

  • Herlev Hospital

Registry information

Official study title

The Effect of Endurance Training on PSA Doubling Time, Body Composition, Insulin Sensitivity and Inflammation in Patients With Prostate Cancer

Important dates

Study start
2008
Primary completion
2012
Study completion
2012
First posted
Apr 25, 2012
Registry last updated
Dec 2, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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