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Completed

NCT Number: NCT03520816

The Effect of Early Physiotherapy on Biochemical Parameters in Major Burn Patients: A Burn Center's Experience

Background: This study planned to investigate the effect of early physiotherapy on biochemical parameters in major burn patients.

Methods: Ten women (50%) and 10 men (50%) aged 21-47 years old were included in our study. Participants were divided into two groups: one group was the treatment group and the other was the control group. In the treatment group, patients were admitted to the physiotherapy programme from the first day they have been hospitalised, in addition to their routine treatment (medical, surgery, etc.), for 4 days per week. It consisted of parameters such as early mobilisation and ambulatory training, chest physiotherapy, and both active and passive normal joint movement exercises. The days of treatment were determined as Tuesday, Wednesday, Thursday and Friday. Patients could not be treated on a Monday because that was surgery day. The control group consisted of patients who could not receive physiotherapy due to various reasons. All patients included in the study were evaluated weekly for 6 weeks after admission to the hospital. Parameters such as demographic information, characteristics of burn injury, C-reactive protein, fibronectin, transferrin and prealbumin were evaluated.

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Key information

Age range

21 year–47 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age ≥ 18 years
  • Major burn injury (according to ABA)
  • Conscious patients

Exclusion criteria

  • Inhalation injury
  • Various chronic disorders
  • Organ dysfunctions

Treatment and study plan

Burn Physiotherapy Protocol

Other

It consisted of parameters such as early mobilisation and ambulatory training, chest physiotherapy, and both active and passive normal joint movement exercises.

Primary outcomes

  1. Fibronectin

    Time frame: Changes in fibronectin at 6 weeks later

    Blood test

  2. Prealbumin

    Time frame: Changes in prealbumin at 6 weeks later

    Blood test

  3. C-reactive protein

    Time frame: Changes in C-reactive protein at 6 weeks later

    Blood test

  4. Transferrin

    Time frame: Changes in transferrin at 6 weeks later

    Blood test

Sponsors and collaborators

Lead sponsor

Hasan Kalyoncu University

Other

Registry information

Important dates

Study start
2016
Primary completion
2017
Study completion
2017
First posted
May 11, 2018
Registry last updated
May 15, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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