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Completed

NCT Number: NCT06270342

The Effect of Dual Task On Upper Extremity Functions In Multiple Sclerosis Patients

The primary aim of this study was to investigate the effect of dual tasking on upper extremity functions in individuals with multiple sclerosis (MS) and compare with healthy controls. Additionally, another aim of our study was to compare the cognitive status, quality of life, fatigue and emotional states of individuals with MS and healthy controls.

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Key information

Conditions

Multiple Sclerosis Autoimmune Diseases Autoimmune Diseases of the Nervous System Demyelinating Autoimmune Diseases, CNS Demyelinating Diseases Immune System Diseases Nervous System Diseases

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Kutahya Health Sciences University

Kütahya, 43100, Turkey (Türkiye)

About this study

The study was carried out at Kutahya Health Sciences University Evliya Çelebi Training and Research Hospital. 30 individuals with MS and 30 healthy controls, aged 18-65, were included in the study. In the evaluation, demographic and clinical data were recorded first. The Minnesota Manual Dexterity Test was used to evaluate the upper extremity function of the participants in single and dual task conditions, and the Dual Task Questionnaire was used to evaluate the difficulties experienced during dual tasks.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Having been diagnosed with Multiple Sclerosis for at least 1 year
  • Being between the ages of 18-65
  • Being at least a primary school graduate
  • Volunteering to participate in the study
  • EDSS score between 1 and 6.5

Exclusion criteria

  • Patients whose Multiple Sclerosis diagnosis is uncertain
  • Having additional neurological disease that may affect clinical evaluation
  • Having a neurological and/or psychiatric disease that may affect cognitive tests
  • Having had an attack in the last 3 months

Treatment and study plan

dual task assessment

Other

The Minnesota Manual Dexterity Test was used to evaluate the upper extremity function of the participants in single and dual task conditions, and the Dual Task Questionnaire was used to evaluate the difficulties experienced during dual tasks. In the dual-task turning test, in addition to the single-task turning test, they were given a cognitive task, the task of counting the months of the year backwards from December to January. The dual-task turning test was continued by changing hands at the end of each turn until the last disk was turned. Meanwhile, verbal fluency and hand errors made while spinning the disc were recorded.

Primary outcomes

  1. The Minnesota Manual Dexterity Test

    Time frame: 30 minutes

    Upper Extremity Function Evaluation. The Minnesota Manual Dexterity Test basically consists of two subtests, the placement and translation test.

    Completing the test faster indicates better dexterity.

  2. Dual Task Questionnaire

    Time frame: 10 minutes

    Dual Task Difficulty Evaluation. The survey consists of 10 items and is scored out of 5 points per question.

    A higher total score indicates worse dual task performance.

  3. Edinburgh Handedness Questionnaire

    Time frame: 10 minutes

    Hand Preference Evaluation. The total scoring is between 100 and -100, individuals with more than 40 points are given right hand; Individuals in this score range from 40 to -40 inclusive are recorded as those who use both hands actively, and individuals with scores of -40 points and below are recorded as left-handed.

  4. Expanded Disability Status Scale

    Time frame: 10 minutes

    Disability Status Evaluation. A score of 0 on the scale indicates normal neurological status, while a score of 10 means MS-related death.

  5. Brief International Cognitive Assessment Battery for Multiple Sclerosis

    Time frame: 15 minutes

    Cognitive Status Evaluation. BICAMS comprises three tests, the Symbol Digit Modalities Test (SDMT), the learning trials of the California Verbal Learning Test II (CVLT-II), and the Brief Visuospatial Memory Test-Revised (BVMT-R).

  6. Beck Depression Scale

    Time frame: 10 minutes

    Emotional Status Evaluation. The lowest score that can be obtained from the scale is 0 and the highest score is 63. According to the resulting total score; It results in absence-mild, mild-moderate, moderate-severe or severe.

  7. Fatigue Impact Scale

    Time frame: 5 minutes

    Fatigue Status Evaluation. Each question receives a score between 0 (no problem) and 4 (maximum problem). The highest score is 160, and higher scores indicate fatigue.

  8. Multiple Sclerosis Quality of Life Questionnaire-54

    Time frame: 15 minutes

    Quality of Life Status Evaluation. The survey contains 54 questions consisting of 12 sections. Added 18 questions are about; general quality of life (2 items), health stress (4 items), sexual functions and satisfaction (5 items), cognitive functions (4 items), energy (1 item), pain (1 item) and social functions (1 item).

Sponsors and collaborators

Lead sponsor

Kutahya Health Sciences University

Other

Registry information

Important dates

Study start
2023
Primary completion
2023
Study completion
2023
First posted
Feb 21, 2024
Registry last updated
Feb 21, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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