The Effect of Docosahexaenoic Acid Supplementation on Biomarkers of Concussion Over the Course of a Year in Canadian National Rugby Players

Nutrition interventions may present a safe and relatively risk free intervention for protection against subconcussive impacts. Docosahexaenoic acid (DHA, 22:6n-3) is the principal Omega 3 polyunsaturated fatty acid in the brain, playing an integral role in the brain's development and structural integrity. The goal of this study is to determine if supplementation with DHA attenuates blood biomarkers of repetitive head trauma linked to sub-concussive impacts sustained in rugby participation.

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Key information

Conditions

Head Trauma Craniocerebral Trauma Nervous System Diseases Trauma, Nervous System Wounds and Injuries

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Texas Christian Universti

Fort Worth, Texas, 76129, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Canadian national rugby athletes on 7s and 15s teams

Exclusion criteria

None

Treatment and study plan

Docosahexaenoic acid (DHA)

Dietary Supplement

Daily administration of docosahexaenoic Acid (DHA). 2 grams of DHA liquid concentrate administered per day throughout trial period.

Other names: Brain Armor DHA Liquid Concentrate

Primary outcomes

Blood concentration of neurofilament light protein

Time frame: 12 times throughout course of 1 year

Concentrations of neuronally derived proteins measured in blood

Sponsors and collaborators

Lead sponsor

Texas Christian University

Other

Registry information

Important dates

Study start: 2017
Primary completion: 2018
Study completion: 2019
First posted: Jul 10, 2018
Registry last updated: Sep 13, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed