The Effect of Dexmedetomidine on Postoperative Analgesia

The purpose of this study is to determine whether additional Dexmedetomidine to patient controlled analgesia can reduce fentanyl consumption.

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Key information

Conditions

Colon Cancer, Rectal Cancer Colonic Diseases Colonic Neoplasms Colorectal Neoplasms Digestive System Diseases Digestive System Neoplasms Gastrointestinal Diseases Gastrointestinal Neoplasms Intestinal Diseases Intestinal Neoplasms Neoplasms Neoplasms by Site Rectal Diseases Rectal Neoplasms

Age range

20 year–74 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Seoul national university hospital

Seoul, 110-744, South Korea

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Elective surgery for colon cancer

Exclusion criteria

Liver disease
Kidney disease
Allergy for study drugs
Inability to receive patient controlled analgesia

Treatment and study plan

Fentanyl

Drug

Fentanyl 2500mcg+NS50ml

Dexmedetomidine

Drug

Fentanyl 2500mcg+Dexmedetomidine 500mcg + NS 45ml

Primary outcomes

total amount of administered fentanyl

Time frame: during first 24 hours after surgery

Sponsors and collaborators

Lead sponsor

Seoul National University Hospital

Other

Collaborators

Pharmbio Korea Co., Ltd.

Registry information

Official study title

Assessment of the Effect of Dexmedetomidine in the Management of Postoperative Pain When Combined With Fentanyl in the Patient-controlled Analgesia

Important dates

Study start: 2011
Primary completion: 2012
Study completion: 2012
First posted: Jun 14, 2011
Registry last updated: Mar 8, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed