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Completed

NCT Number: NCT01929694

The Effect of Consuming a guaraná and Vitamin/Mineral Complex Pre-exercise on Affect, Exertion, Metabolism and Cognition

Consuming a guaraná and vitamin and mineral complex can improve mental fatigue and cognitive function at rest; guaraná also contains caffeine, which can reduce perceived exertion and increase fat burning during exercise. The purpose of this study is to test whether consuming a guaraná and vitamin and mineral product before exercise influences affect (mood), physical exertion and fat burning during exercise and mental fatigue, cognitive performance and affect post-exercise.

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Key information

Age range

18 year–35 year

Sex eligibility

Male

Study type

Interventional

Phase

Phase 4

Primary location

Brain, Performance and Nutrition Research Centre, Northumbria Univerity

Newcastle upon Tyne, Tyne and Wear, NE18ST, United Kingdom

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Individuals must be:

  • Healthy
  • Male
  • Aged between 18 and 35years
  • Habitually active (exercising at least twice a week)
  • Able to run at a moderate pace for 30 minutes non-stop on a treadmill

Exclusion criteria

Individuals will not be eligible to take part in this study if they:

  • have a history of neurological or psychiatric diseases excluding anxiety or depression
  • have a current diagnosis of depression or anxiety
  • have a history of significant head trauma, metabolic, endocrine or cardiac disorders
  • have smoked within the last 3 months,
  • have high blood pressure >140/90mmHg
  • consume > 500 mg caffeine per day from all dietary sources
  • have adverse reactions to caffeine containing products (i.e. tea, coffee, energy drinks, cola, Pepsi)
  • are currently taking any pharmaceuticals
  • have habitual taken dietary supplements within the last 4 weeks (defined as ≥3 consecutive days or ≥4 days in total per week)
  • have current or history of drug or alcohol abuse
  • have participated in another clinical trial within 30 days prior to screening
  • have any condition which may interfere with your ability to perform assessments
  • have any history of hypersensitivity to the investigational product or its active or inactive constituents or any food allergy or intolerance

Treatment and study plan

Berocca Boost

Dietary Supplement

Placebo

Dietary Supplement

Primary outcomes

  1. Affect

    Time frame: Assessed pre-exercise, at 10min intervals during exercise and 45 and 75min post-exercise

    Affect measured using the Feeling Scale and Felt Arousal Scale

Secondary outcomes

  1. Exertion

    Time frame: Measured at 10min intervals during exercise

    Rate of perceived exertion measured using the Borg scale

Other outcomes

  1. Cognitive Function

    Time frame: Assessed at baseline, pre-exercise and immeadiately and 75min post-exercise

    Participants will complete a set of cognitive tasks (Immediate Word Recall, Choice Reaction Time, Rapid visual information processing task, Numeric Working Memory, Delayed word Recall, Word Recognition and Picture Recognition) measuring episodic memory, working memory, attention and decision making.

  2. Mood

    Time frame: Assessed at baseline, pre-exercise and immeadiately and 75min post-exercise

    Assessed using the Bond-Lader Visual Analogue Scales (VAS) and Energy VAS (concentration, physical stamina, mental stamina)

  3. Substrate Metabolism

    Time frame: Measured at 10min intervals during exercise

    Measured using an online gas analysis system (Cortex). Oxygen uptake, carbon dioxide production, fat and carbohydrate oxidation and energy expenditure will be measured for 1 min at each 10min interval.

Sponsors and collaborators

Lead sponsor

Northumbria University

Other

Collaborators

  • Bayer

Registry information

Official study title

The Effect of Consuming a Guaraná and Vitamin and Mineral Complex Before a Morning Exercise Session on Affect, Exertion and Substrate Metabolism During Exercise and Cognitive Performance During the Post-exercise Recovery Period

Important dates

Study start
2013
Primary completion
2014
Study completion
2014
First posted
Aug 28, 2013
Registry last updated
Oct 3, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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