The Effect of Cold Storage Solutions on Ischemic Injury in Lung Transplantation

The purpose of this study is to compare 2 different cold storage solutions, used to preserve donor lungs for lung transplantation, and their effect on cytokine activation related to ischemic reperfusion injury. Primary endpoint is 30 day survival.

Completed

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Key information

Conditions

Lung Transplant Recipients

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 3

About this study

The length of ischemic time in harvesting lung allografts is associated with graft survival. It is further thought that ischemic changes in early post-transplantation bronchoscopic biopsies has a direct correlation with later development of chronic rejection.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Any patient undergoing a lung trasnplant at Johns Hopkins Hospital -

Exclusion criteria

Treatment and study plan

Celsior Cold Storage Solution

Device

Sponsors and collaborators

Lead sponsor

Johns Hopkins University

Other

Registry information

Official study title

A Prospective, Controlled, Randomized Study on the Effect of Cold Storage Solutions on Complement Activation and Other Mediators of Ischemic Injury in Lung Transplantation

Important dates

Study start: 2000
Study completion: 2005
First posted: Feb 1, 2006
Registry last updated: Sep 28, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed