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NCT Number: NCT06818370

The Effect of Coconut Oil on Alopecia

İn this study will be conducted to evaluate the effect of coconut oil on alopecia in 86 female breast cancer patients treated at Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital between 01.02.2025-31.12.2025.

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Key information

Conditions

Breast Cancer Alopecia Breast Diseases Breast Neoplasms Hair Diseases Hypotrichosis Neoplasms Neoplasms by Site Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Skin Diseases Skin and Connective Tissue Diseases

Age range

18 year–65 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Dr. Abdurrahman Yurtaslan Ankara Onkoloji Eğitim ve Araştırma Hastanesi

Ankara, Yenimahalle, 06170, Turkey (Türkiye)

Location status: Recruiting

About this study

Cancer is a disease in which the cells in our body multiply uncontrollably and develop by metastasizing, and the symptoms, course and consequences of the disease can show complex qualities in each patient. Cancer treatments have benefits and harms. One of these side effects is alopecia.

Alopecia due to cancer treatments is a condition of hair loss, partial or complete, usually temporary but rarely permanent.

In chemotherapy-induced alopecia, the hair follicle is damaged due to the pause in the anagen phase and causes the hair to break off spontaneously during activities such as washing and brushing the hair.

Various scales are used in the evaluation of alopecia due to cancer treatments, such as the National Cancer Institute Common Terminology Criteria for Side Effects and the Dean Alopecia Scale.

Some applications are made to prevent and treat alopecia. These include strategies and pharmacological applications to physically reduce the amount of medication given to the hair follicle.

Coconut oil helps regrow damaged hair. It provides essential proteins necessary for hair and softens the scalp and hair.

In the literature, it has been observed that studies showing the effects of coconut oil for the prevention and treatment of alopecia are insufficient. This study will be conducted on 86 breast cancer patients to determine the effect of coconut oil on the development of alopecia.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • • To have been diagnosed with breast cancer.
  • The chemotherapy treatment plan should be planned as the Doxorubicin-Cyclophosphamide protocol.
  • Volunteer to participate in the study.
  • Be 18 years of age or older.
  • Being a woman.

Exclusion criteria

  • • Having any health problem or disability that prevents communication (vision-hearing problems, neurological, psychiatric diseases).
  • Planning other treatments other than the Doxorubicin-Cyclophosphamide protocol for the treatment of breast cancer.
  • Not volunteering to participate in the study.
  • Having previously experienced any disease/skin problem that causes hair loss.
  • Having received chemotherapy before.

Treatment and study plan

Coconut oil

Other

The coconut oil application protocol will be explained to the patients in the experimental group and 10 milliliters of coconut oil will be applied to the hair follicles once a week. Alopecia assessment will be done every week.

Primary outcomes

  1. National Cancer Instute (NCI) Common Terminology Criteria for Adverse Events (CTCAE); Alopecia

    Time frame: 1-12 WEEK

    Grade 1; Hair loss of <50% of normal for that individual that is not obvious from a distance but only on close inspection; a different hair style may be required to cover the hair loss but it does not require a wig or hair piece to camouflage Grade 2; Hair loss of >=50% normal for that individual that is readily apparent to others; a wig or hair piece is necessary if the patient desires to completely camouflage the hair loss; associated with psychosocial impact

Study contacts

Contact information is provided by the study sponsor or research team.

İsmail Dakdevir, Nurse

CONTACT

[email protected]

+905533228416

Sponsors and collaborators

Lead sponsor

Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

Other

Collaborators

  • Çankırı Karatekin University

Registry information

Official study title

The Effect of Coconut Oil on Alopecia in Women Receiving Doxorubucin-Cycylophosphamide Treatment for Breast Cancer

Important dates

Study start
2025
Primary completion
2025
Study completion
2026
First posted
Feb 10, 2025
Registry last updated
Feb 12, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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