Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT07375836

The Effect of Chocolate Consumption During Labor on Second Stage Duration

Childbirth is an energy-intensive physiological process, requiring sustained effort comparable in intensity to moderate physical activity. Studies suggest that providing an available energy source during labor, such as dextrose infusion or natural carbohydrate-rich foods such as dates, may shorten the duration of labor and improve cervical dilation without adversely affecting obstetric outcomes. The primary objective of the study is to examine whether giving chocolate during labor affects the duration of the second stage of labor, compared to a control group that will not receive a nutritional intervention. The study is a prospective, randomized, controlled trial that will be conducted in the delivery room of Hillel Yaffe Medical Center. Healthy pregnant women with a singleton pregnancy at ≥37 weeks gestational age, in spontaneous or induced labor, without diabetes (pre/gestational), will be recruited to participate. Participants in the intervention group will receive one serving of 50 grams of milk chocolate (cocoa content 25-30%, without filling or additives) at a cervical dilation of 6 cm or more (and not yet fully dilated). The mother will be asked to consume the serving gradually over 30 minutes. Milk chocolate was chosen because it is better tolerated compared to dark chocolate, has a more gentle profile of active ingredients (which can increase nausea and heartburn) and provides a source of available carbohydrates. The study will be conducted in accordance with the guidelines of the Ministry of Health's procedure for medical experiments on humans, and will be conducted after approval by the Institutional Helsinki Committee.

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Age range

18 year–50 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Gestational age ≥37 weeks
  • Single fetus in cephalic presentation
  • Spontaneous or induced labor in the active phase (dilation ≥ 5 cm).
  • Normal assessment of the mother and fetus upon admission to the delivery room (normal indices, normal monitoring and biophysical profile)
  • BMI 18-35 -

Exclusion criteria

  • Multiple pregnancies
  • Gestational age <37 weeks
  • Gestational or pre-gestational diabetes
  • Significant underlying diseases
  • Previous cesarean section/myomectomy
  • Known significant fetal malformation
  • Sensitivity to chocolate ingredients
  • Lack of documentation of necessary information -

Treatment and study plan

50 g of milk chocolate cocoa content 25-30%

Other

Milk chocolate was chosen as it is better tolerated compared to dark chocolate, has a milder profile of active ingredients (which can increase nausea and heartburn) and provides a source of available carbohydrates.

A dose of 50 grams was chosen that provides 25-30 grams of simple carbohydrates - sufficient for a significant increase in blood glucose but low enough to prevent a sudden sugar load or nausea.

The intervention will be given at 6-9 cm dilation, towards the transition to the second phase - to allow the absorption of glucose and neurochemicals to be deafened at a time when the body needs increased energy and alertness. Giving it earlier may result in the effect of the chocolate wearing off before the second phase, and later - there will be no time for effective absorption.

Primary outcomes

  1. Duration of second stage of labor

    Time frame: From full cervical dilation to delivery

    The duration of the second stage of labor, defined as the time in minutes from full cervical dulation (10cm) to delivery of the neonate.

Secondary outcomes

  1. Mode of delivery

    Time frame: At delivery

    Mode of delivery categorized as spontanous vaginal delivery, operative vaginal delivery (vacuum), or cesarean delivery

  2. Maternal nausea or vomiting during labor

    Time frame: From intervention administration untill discharge from labor room

    The occurrence of maternal nausea or vomiting during labor following the assigned intervention, as documented in the medical record

  3. Neonatal Apgar score at 1 and 5 minutes

    Time frame: 1 and 5 minutes after delivery

    The Apgar score is assessed at 1 and 5 minutes after delivery. The total score ranges from 0 to 10, with higher scores indicating better neonatal condition.

  4. Umbilical cord blood glucose level

    Time frame: at delivery

    Umbilical cord blood glucose concentration measured from umbelical blood collected immediately after delivery (when a cord blood sample is obtained per routine practice

  5. Maternal heart rate

    Time frame: During the second stage of labor

    Maternal heart rate measured in beats per minute as recorded by continous intrapartum maternal monitorind

  6. Umbelical cord blood PH

    Time frame: At delivery

    Umbelical cord blood PH measures immediatley after delivery

Study contacts

Contact information is provided by the study sponsor or research team.

Libby O Madar, M.D

CONTACT

[email protected]

+972-4-7744602

Rinat Gabbay-Benziv, M.D

CONTACT

+972-4-7744514

Sponsors and collaborators

Lead sponsor

Hillel Yaffe Medical Center

Other Gov

Registry information

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Jan 29, 2026
Registry last updated
Feb 4, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.