Enrolling by Invitation

NCT Number: NCT07128043

The Effect of Cassava Waxes Hot Bath on Pain, Pressure Pain Threshold and Hand Function Among Patients With Trigger Finger

Objective: This study aimed to evaluate the efficacy of cassava wax hand immersion combined with ultrasound therapy on pain severity, pain threshold, finger locking frequency, and hand functional ability in patients with trigger finger. We assessed immediate, short-term, and long-term treatment outcomes.

Methods: This was a randomized controlled trial. Thirty-eight eligible volunteers were randomly assigned to two groups. The experimental group received ultrasound therapy combined with cassava wax hand immersion, while the control group received ultrasound therapy alone. Treatments were administered three times per week for four weeks.

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Key information

Conditions

Patients With Trigger Finger

Age range

40 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Narongsak Khamnon

Chiang Rai, Tha Sut, 57100, Thailand

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Having a diagnosis of trigger finger by a physician or a specialized physical therapist
Present with all of the following symptoms: pain at the base of the affected finger, triggering (catching/locking) as a primary symptom (though pain often increased with it), and a palpable or audible triggering sensation during finger flexion and extension.
Able to understand and follow the research procedures.

Exclusion criteria

Having a history of neurological conditions, such as stroke or diseases causing sensory impairment in the upper limbs.
Having arthritis or infection in the upper limbs
Having Rheumatoid Arthritis.
Having a skin condition in the wrist or hand area, upper limb fractures within the last 6 months, or those affecting movement.
Having musculoskeletal deformities of the upper limbs that impact movement.
Having an inflammation (e.g., pain, swelling, redness, warmth) in the wrist and fingers
Having a history of upper limb surgery, an allergy to cassava starch/flour.

Treatment and study plan

ultrasound therapy and cassava wax hot immersion

Device

participants sat in a comfortable position with their hand placed on a pillow or cushion. Ultrasound gel was applied to the base of the painful finger, and ultrasound therapy was performed for 5 minutes at a frequency of 3 MHz and an intensity of 0.5-1 W/cm. Afterward, the hand was cleaned and immersed in cassava wax heated to 125°F (51.7°C). The affected hand was dipped into the wax for 3 seconds, then removed. This process was repeated for 10 cycles. The hand was then wrapped in a plastic bag and a towel for 15 minutes before the wax was removed and peeled off.

Ultrasound therapy

Device

ultrasound therapy Ultrasound gel was applied to the base of the painful finger, and ultrasound therapy was performed for 5 minutes at a frequency of 3 MHz and an intensity of 0.5-1 W/cm.

Primary outcomes

Visual Analog Scale (VAS)

Time frame: - Time 1: Baseline or Day 1 - Time 2:After treatment, the first time of immediate effect - Time 3: After treatments in 4 weeks - Time 4: 1 month after finishing treatments in 4 weeks.

This assesses the current pain severity using a 10-centimeter scale. Scores range from 0 to 10, where the far left end of the scale indicates "no pain at all" (score of 0), and the far right end indicates "worst pain imaginable" (score of 10). Participants were asked to mark an 'X' on the scale at the point corresponding to their current pain severity.
Pressure pain threshold

Time frame: - Time 1: Baseline or Day 1 - Time 2:After treatment, the first time of immediate effect - Time 3: After treatments in 4 weeks - Time 4: 1 month after finishing treatments in 4 weeks.

Participants were seated, and the assessor identified the location of the myofascial trigger point. This spot was marked with a washable pen. An algometer (a device used to measure pain threshold) was then applied to the marked trigger point at a rate of approximately 1 kg/second. Participants were instructed to signal immediately upon feeling the onset of pain (pain threshold). The applied pressure ranged from 0 to 11 kg/cm. Each participant underwent three measurements, with a 3-minute rest interval between each. The average of these three measurements was then calculated.
Pain frequency

Time frame: - Time 1: Baseline or Day 1 - Time 2: After treatments in 4 weeks - Time 3: 1 month after finishing treatments in 4 weeks.

Participants were interviewed regarding the frequency of finger locking symptoms and the number of finger locking episodes per day.
Disability of the arm, shoulder and hand

Time frame: - Time 1: Baseline or Day 1 - Time 2: After treatments in 4 weeks - Time 3: 1 month after finishing treatments in 4 weeks.

This is a questionnaire designed to assess the level of upper extremity impairment. It evaluates the functional ability of the wrist and finger joints, comprising 30 questions related to the patient's daily life activities and work capacity.

Sponsors and collaborators

Lead sponsor

University of Phayao

Other

Registry information

Official study title

The Effect of Cassava Waxes Hot Bath on Pain, Pressure Pain Threshold and Hand Function Among Patient With Trigger Finger: Single-Blind Randomized Controlled Trial Study

Important dates

Study start: 2025
Primary completion: 2025
Study completion: 2025
First posted: Aug 17, 2025
Registry last updated: Aug 17, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.