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OpenTrials
Completed

NCT Number: NCT03245502

The Effect of Blood Transfusion on Venoarterial PCO2 Difference in Cardiac Surgery

Venoarterial CO2 difference(delta PCO2), lactate, central venous oxygen saturation(ScVO2) will be recorded in several steps in coronary artery bypass graft and valvular cardiac operations. The patients will be divided into two groups as Transfused, and Non-Transfused Groups observationally. The trend of delta CO2, lactate, ScVO2, postoperative creatinine values, postoperative complications and 28 days mortality will be compared.

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Key information

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Turkiye Yuksek Ihtisas Education and Research Hospital

Ankara, 06230, Turkey (Türkiye)

About this study

Preoperative creatinine values, demographic data, comorbidities will be recorded in ASA I-II elective coronary artery and valvular cardiac surgery patients. Intraoperative delta PCO2, lactate, ScVO2 will be recorded in several steps. The patients will be divided into two groups as Transfused, and Non-Transfused Groups observationally. The trend of delta CO2, lactate, ScVO2, postoperative creatinine values, postoperative complications and 28 days mortality will be compared.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Elective cardiac surgery, stable cardiac function

Exclusion criteria

  • Clinical signs of heart failure, symptomatic cerebral or peripheral failure, uncontrolled diabetes mellitus

Treatment and study plan

Blood transfusion

Biological

The transfusion of erythrocyte suspension

Primary outcomes

  1. Complication

    Time frame: 5 days

    The postoperative neurologic, renal, hepatic, respiratory complications

Secondary outcomes

  1. Mortality

    Time frame: 28 days

    mortality

Sponsors and collaborators

Lead sponsor

Turkiye Yuksek Ihtisas Education and Research Hospital

Other Gov

Registry information

Important dates

Study start
2017
Primary completion
2017
Study completion
2017
First posted
Aug 10, 2017
Registry last updated
Dec 18, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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