Skip to main content
OpenTrials
Completed

NCT Number: NCT03736304

The Effect of Automated Electronic Alert for Acute Kidney Injury on the Outcomes of Hospitalized Patients

Acute kidney injury (AKI) is a common disease, but diagnosis is usually delayed or missed in hospitalized patients. The automated electronic alert for AKI may help to improve the outcomes of these patients through identifying all cases of AKI early. Therefore, the investigators conduct a randomly controlled study to test whether automated electronic alert for AKI could improve the outcomes of hospitalized patients.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Acute Kidney Injury Disease Early Diagnosis Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Kidney Diseases Male Urogenital Diseases Outcomes Pathologic Processes Pathological Conditions, Signs and Symptoms Renal Insufficiency Urogenital Diseases Urologic Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Jiangsu Province Hospital

Nanjing, Jiangsu, 210029, China

About this study

Acute kidney injury (AKI) is a common disease, but diagnosis is usually delayed or missed in hospitalized patients. The automated electronic alert for AKI may help to improve the outcomes of these patients through identifying all cases of AKI early. Therefore, the investigators conduct a randomly controlled study to test whether automated electronic alert for AKI could improve the outcomes of hospitalized patients.

The patients were randomly divided into two groups:

Usual care : patients will receive standard clinical care by the primary physicians AKI alert : an AKI alert will be sent to the doctor in charge. The team of kidney experts would give a suggestion if the doctor in charge need a renal consultation.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Hospitalized adult patients with an Alert for AKI(based on KDIGO guidelines)

Exclusion criteria

  • Patients already having eGFR<15ml/min/1.73m2 or receiving renal replacement therapy for AKI at the time of alert.
  • Patients already having a AKI before admission.

Treatment and study plan

AKI alert

Device

An AKI alert will send to the doctor in charge. The team of nephrologists would give suggestions if the doctor in charge need a renal consultation.

Usual Care

Other

Patients will receive standard clinical care by the doctor in charge.

Primary outcomes

  1. Estimated glomerular filtration rate changed within 7 days

    Time frame: within 7 days diagnosed with AKI

    Medical record

Secondary outcomes

  1. seven-day mortality

    Time frame: within 7 days diagnosed with AKI

    Medical record

  2. 30-day mortality

    Time frame: within 30 days diagnosed with AKI

    Medical record

  3. 1-year mortality

    Time frame: within 1 year diagnosed with AKI

    telephone follow-up

  4. receiving renal replacement therapy at seventh day

    Time frame: 7 days

    Medical record

  5. receiving renal replacement therapy at 30th day

    Time frame: 30 days

    telephone follow-up

  6. receiving renal replacement therapy at 1 year

    Time frame: 1 year

    telephone follow-up

  7. the rate of stage 2 AKI

    Time frame: within 7 days diagnosed with AKI

    Medical record

  8. the rate of stage 3 AKI

    Time frame: within 7 days diagnosed with AKI

    Medical record

  9. the rate of AKI recovery at 90 day

    Time frame: 90 days

    telephone follow-up

  10. the rate of timely-recognition of AKI

    Time frame: 3 days

    Medical record

  11. the interventions for AKI

    Time frame: within 7 days diagnosed with AKI

    Medical record

  12. Follow-up rate after discharge

    Time frame: 1 year

    telephone follow-up

Sponsors and collaborators

Lead sponsor

The First Affiliated Hospital with Nanjing Medical University

Other

Registry information

Official study title

The Effect of Automated Electronic Alert for Acute Kidney Injury on the Outcomes of Hospitalized Patients: a Single Center Randomized Controlled Trial.

Important dates

Study start
2019
Primary completion
2022
Study completion
2022
First posted
Nov 9, 2018
Registry last updated
Jan 2, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.