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NCT Number: NCT06370286

The Effect of Acute Concurrent Exercise on Inhibitory Control: An Event-related Potential Study

The present study aimed to determine the effects of acute concurrent exercise on inhibitory control via behavioral and event-related potential approaches and to examine its potential mediational role on lactate among younger adults. The main questions it aims to answer are: (1) Does acute concurrent exercise improve inhibitory control via behavioral and event-related potential approaches? (2) Does lactate play a potential mediational role in the effect of acute concurrent exercise on inhibitory control?

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Key information

Conditions

Exercise Behavior Cognition Motor Activity

Age range

20 year–30 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Department of Physical Education and Sport Sciences, National Taiwan Normal University

Taipei, 106, Taiwan

About this study

The present study aimed to determine the effects of acute concurrent exercise (CE) on inhibitory control via behavioral and event-related potential approaches and to examine its potential mediational role on lactate. Participants were randomly assigned to either a CE, aerobic exercise (AE), or control (CON) group. Participants in the CE group engaged in 12-minutes of AE (40%-59% of heart rate reserve [HRR]) coupled with 13-minutes of resistance exercise (1 set, with 75% of 10-repetition maximum, and 12 repetitions of 8 movements). The AE group participated in 25 minutes of AE (40%-59% HRR). Prior to and following exercise onset, participants in both the CE and AE groups completed a 5-minute warm-up and cool-down. Participants in the CON group read books for 35 minutes. Lactate concentrations were measured at timepoint of 0-, 17-, and 30-minutes relative to the treatment onset. Response time (RT) and accuracy in the Stroop test, as well as P3 amplitudes, were assessed before and after the treatment.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • aged between 20 and 30 years
  • able to exercise without undue risk (i.e., the first seven questions of the Physical Activity Readiness Questionnaire for Everyone [PAR-Q+] were answered "No")
  • right-handed dominance
  • typical or corrected-to-typical eyesight
  • limited physical activity in the previous month (i.e., < 150 minutes/week of moderate-intensity physical activity)

Exclusion criteria

  • psychiatric or neurological ailments
  • cardiorespiratory or neuromuscular conditions
  • obese status (body mass index [BMI] > 27 kg/m2)

Treatment and study plan

concurrent exercise (CE)

Behavioral

Participants in the concurrent exercise group engaged in 12-minutes of aerobic exercise (40%-59% of heart rate reserve [HRR]) coupled with 13-minutes of resistance exercise (1 set, with 75% of 10-repetition maximum, and 12 repetitions of 8 movements). Prior to and following exercise onset, participants completed a 5-minute warm-up and cool-down.

Aerobic Exercise (AE)

Behavioral

Participants in the aerobic exercise (AE) group participated in 25 minutes of AE (40%-59% of heart rate reserve [HRR]). Prior to and following exercise onset, participants completed a 5-minute warm-up and cool-down.

Primary outcomes

  1. Inhibitory control

    Time frame: 30 minutes

    Inhibitory control was assessed using a modified computerized version of the Stroop test, which was administered through Neuroscan Stim2 software (Compumedics Neuroscan, Charlotte, NC). The test comprised four blocks, each consisting of 108 trials. Within each block, three types of trials were presented: neutral, congruent, and incongruent. The neutral trial involved displaying a square printed in red, green, or blue color. The congruent trial presented Chinese language prints in corresponding colors and words [i.e., 紅 (RED), 綠 (GREEN), or 藍 (BLUE)]. In contrast, the incongruent trial displayed Chinese language prints in different colors and words [e.g., 紅 (RED) printed in blue color]. Each block included 36 neutral trials, 36 congruent trials, and 36 incongruent trials. Participants were instructed to respond promptly and accurately to the color of the stimulus presented. Subsequently, the mean response time (RT) of correct trials and accuracy for each Stroop condition were examined.

Secondary outcomes

  1. Blood lactate

    Time frame: Timepoint 1 (prior to the commencement of treatment), Timepoint 2 (17 minutes after the initiation of treatment), and Timepoint 3 (30 minutes after the start of treatment).

    Blood lactate levels were assessed using fingertip samples measured with a lactate analyzer (The EDGE, Taipei, Taiwan) at three distinct time points: Timepoint 1 (prior to the commencement of treatment), Timepoint 2 (17 minutes after the initiation of treatment), and Timepoint 3 (30 minutes after the start of treatment).

Sponsors and collaborators

Lead sponsor

National Taiwan Normal University

Other

Registry information

Important dates

Study start
2021
Primary completion
2021
Study completion
2022
First posted
Apr 17, 2024
Registry last updated
Apr 18, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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