Skip to main content
OpenTrials
Completed

NCT Number: NCT05314634

The Effect of Acute Concurrent Exercise on Executive Function: An Event-Related Potential Study

Executive function is a high-level cognition which plays an important role in our life. Meta-analysis study has demonstrated that acute exercise could improve executive function. However, it is still unclear whether executive function can be enhanced by the concurrent exercise that combines aerobic and resistance exercise. Moreover, previous studies indicated that acute exercise could increase the concentration of blood lactate which is positive correlated to executive function. It is still unclear whether the effect of acute concurrent exercise on executive function is mediated by blood lactate. Therefore, the purposes of present study are: (1) Measuring the effect of acute concurrent exercise and aerobic exercise on executive function. (2) Measuring whether the effect of acute concurrent exercise on executive function is mediated by blood lactate.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Age range

21 year–28 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Department of Physical Education and Sport Sciences, National Taiwan Normal University

Taipei, 106, Taiwan

About this study

Executive function is a high-level cognition which plays an important role in academic performance, career, and interpersonal relationship. Meta-analysis study has demonstrated that acute exercise could improve executive function, and also observed similar positive effect through both aerobic and resistance exercise. However, it is still unclear whether executive function can be enhanced by the concurrent exercise that combines aerobic and resistance exercise. Moreover, previous studies indicated that acute exercise could increase the concentration of blood lactate which is positive correlated to executive function. It is still unclear whether the effect of acute concurrent exercise on executive function is mediated by blood lactate. Therefore, the purposes of present study are: (1) Measuring the effect of acute concurrent exercise and aerobic exercise on executive function. (2) Measuring whether the effect of acute concurrent exercise on executive function is mediated by blood lactate.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • no history of psychiatric or neurological disorders
  • no history of cardiovascular disease
  • normal or corrected to normal vision and normal color perception
  • right handed
  • 18.5 < BMI < 27

Exclusion criteria

  • Diagnosed with epilepsy

Treatment and study plan

Concurrent exercise

Behavioral

Participants conduct warm up for 5-min, aerobic exercise for 12-min, resistance exercise for 13-min, and 5-min cool down.

Aerobic Exercise

Behavioral

Participants conduct warm up for 5-min, resistance training for 25-min, and 5-min cool down.

Primary outcomes

  1. Task Switch Test Response Times

    Time frame: 30 minutes

    The shifting aspect of executive function was assessed using a computerised task-switching test. Each participant (N=78) completed 384 trials across six blocks (64 trials per block). The test consisted of two types of cognitive tasks: (1) number magnitude judgment (greater/less than 5) for digits 1-9 presented in solid-line squares, and (2) odd/even judgment for numbers presented in dotted-line squares. Performance was analysed by calculating each participant's mean response time (milliseconds) under four conditions:

    Homogeneous condition: Blocks where participants performed the same task repeatedly (Blocks 1 & 2, e.g., AAAA or BBBB) Heterogeneous condition: Blocks where tasks were mixed (Blocks 3-6, e.g., AABBAA) Non-switch trials: Consecutive trials of the same task type within heterogeneous blocks (e.g., AA or BB) Switch trials: Trials where the task changed from the previous trial within heterogeneous blocks (e.g., AB or BA) Lower response time represents better task perform

Other outcomes

  1. Blood Lactate

    Time frame: before intervention, 17 minutes after intervention, and immediately after the 35 minute intervention

    The lactic acid system is one of the important systems of human energy metabolism. In addition to supplying energy to muscles, it can also be used as an energy source for brain energy metabolism. When people doing exercise, the concentration of blood lactate will be increased, and the lactate acid system will replace the glucose system as the main energy source for the brain. In the present study, blood lactate were collected from fingertip with a lancet and measured by lactate analyzer before, 17 minutes after, and after intervention.

  2. Stroop Task

    Time frame: 30 minutes

    The Stroop task consists of neutral, congruent, and incongruent trials. In neutral trials, colored rectangles were presented and participants were instructed to respond to whether the squares were red, blue, or green. For congruent and incongruent trials, participants were presented with the names of the three Chinese color words of 紅 (red), 藍 (blue), or 綠 (green) printed in either the same (congruent) or different (incongruent) ink color and instructed to respond to the color of the ink while inhibiting the meaning of the word.

Sponsors and collaborators

Lead sponsor

National Taiwan Normal University

Other

Registry information

Important dates

Study start
2021
Primary completion
2021
Study completion
2022
First posted
Apr 6, 2022
Registry last updated
Feb 20, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.