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OpenTrials
Completed

NCT Number: NCT03063346

The Effect of a Protein Hydrolysate on Muscle Strength Recovery

Overtraining is a real problem for (semi-)professional athletes. Overtraining is often caused by the bodies' lack of ability to recover between training. In addition, during high intensity training reactive oxygen species are formed up to 20 fold compared to resting values. This causes increased muscle tissue damage after intense exercise, which slows down recovery. Improving recovery may increase an athlete's ability to reach higher training volumes resulting in establishing a higher performance plateau.

It is known that hydrolyzed proteins have a positive effect on muscle protein synthesis due to its faster absorption rate. Therefore, it is hypothesized that a known protein hydrolysate may have positive effects on strength recovery.

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Key information

Conditions

Muscle Strength Recovery

Age range

18 year–35 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy individuals (based on their medical history provided during a general health questionnaire)
  • Participants are amateur or (semi-) professional athletes in resistance or interval sports (engage in >6 hours of intense physical activity per week).
  • Age 18 - 35
  • Experience in resistance training

Exclusion criteria

  • Use of creatine supplements and/or anabolic steroids.
  • Allergy to test product/protein
  • Allergy to specific protein hydrolysate
  • BMI lower than 18 or higher than 30.
  • Lack of technique in correctly performing a barbell squat (judged by sports physiologist).
  • Recent muscle injury in legs or back less than one month before the start of the study.
  • Cardiovascular complications
  • Use of medication
  • Administration of investigational drugs or participation in any scientific intervention study which may interfere with this study (to be decided by the principle investigator), in the 180 days prior to the study.
  • Abuse of products; alcohol (> 20 alcoholic units per week) and drugs

Treatment and study plan

Protein hydrolysate high dose

Dietary Supplement

Protein hydrolysate low dose

Dietary Supplement

Placebo

Dietary Supplement

Primary outcomes

  1. Muscle strength recovery

    Time frame: 4 weeks

    difference in peak force between the exhaustion challenge and the recovery challenge, measured with a linear encoder during a squat exercise

Secondary outcomes

  1. Blood lactate buildup

    Time frame: 4 weeks

    in mmol/L, measured trough a finger prick after exhaustion and recovery challenge

  2. Body composition

    Time frame: 4 weeks

    fat percentage, based on 4-point skin fold measurement

  3. Exercise volume

    Time frame: 4 weeks

    amount of repetitions x time taken x power, measured with a linear encoder during squat exercise

  4. Peak force output

    Time frame: 4 weeks

    measured with a linear encoder during the squat exercise

Sponsors and collaborators

Lead sponsor

Bioactor

Other

Registry information

Official study title

The Effect of a Protein Hydrolysate on Muscle Strength Recovery in Athletes

Important dates

Study start
2016
Primary completion
2017
Study completion
2017
First posted
Feb 24, 2017
Registry last updated
Mar 3, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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