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Completed

NCT Number: NCT02016404

The Effect of a Low Sodium-High Potassium Salt on Blood Pressure in Vietnamese Adults

The purpose of this study was to investigate the effects of low-sodium, high-potassium condiments and salt on blood pressure in untreated (pre)hypertensive Vietnamese adults.

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Key information

Conditions

Hypertension Cardiovascular Diseases Vascular Diseases

Age range

45 year–64 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

National Institute of Nutrition (NIN), Department of Community Nutrition

Hanoi, Hai Ba Trung Dist., Vietnam

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Untreated prehypertension or mild hypertension (systolic BP between 130 and 160 mmHg and/or diastolic BP between 85 and 100 mmHg) based on the mean of two measurements with a 1-week interval

Exclusion criteria

Diagnosed or self-reported cardiovascular disease Diagnosed or self-reported kidney disease

Treatment and study plan

Low-sodium, high-potassium salt

Other

Iodized low-sodium, high-potassium botcanh (a traditional mixture of salt, MSG, sugar and herbs) plus and iodized low-sodium, high-potassium salt for home food preparation

Regular salt

Other

Regular iodized high-sodium botcanh (a traditional mixture of salt, MSG, sugar and herbs) and high-sodium salt

Primary outcomes

  1. Change in office systolic blood pressure (SBP)

    Time frame: Change during 8 weeks of intervention

    Based on repeated measurements with a digital BP device (OMRONHEM 762) using the standard protocol of WHO STEP guideline at week 0, 2, 4 6 and 8.

Secondary outcomes

  1. Change in office diastolic blood pressure (DBP)

    Time frame: Change during 8 weeks of intervention

    Based on repeated measurements with a digital BP device (OMRONHEM 762) using the standard protocol of WHO STEP guideline at week 0, 2, 4, 6 and 8.

Other outcomes

  1. Change in 24-hour urinary sodium excretion

    Time frame: Change during 8 weeks of intervention

  2. Change in 24-hour urinary potassium excretion

    Time frame: Change during 8 weeks of intervention

  3. Change in body weight

    Time frame: Change during 8 weeks of intervention

  4. Change in 24-hour urinary calcium excretion

    Time frame: Change during 8 weeks of intervention

  5. Change in 24-hour urinary iodine excretion

    Time frame: Change during 8 weeks of intervention

  6. Change in 24-hour urinary creatinine excretion

    Time frame: Change during 8 weeks of intervention

  7. Change in 24-hour urinary protein

    Time frame: Change during 8 weeks of intervention

  8. Change in heart rate

    Time frame: Change during 8 weeks of intervention

Sponsors and collaborators

Lead sponsor

Wageningen University

Other

Collaborators

  • National Institute of Nutrition, Vietnam

Registry information

Important dates

Study start
2013
Primary completion
2013
Study completion
2013
First posted
Dec 20, 2013
Registry last updated
Dec 20, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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