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OpenTrials
Completed

NCT Number: NCT05943405

The Disease Severity In Patients With Psoriasis

This observational study aims to evaluate new markers to predict disease activity in psoriasis. The main question is SGOT, SGPT, GGT, hs-CRP, and apo B related to disease severity in psoriasis.

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Key information

Conditions

Psoriasis Skin Diseases Skin Diseases, Papulosquamous Skin and Connective Tissue Diseases

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Universitas Sebelas Maret Hospital

Sukoharjo, Central Java, 57161, Indonesia

About this study

Psoriasis patients who had signed an informed consent were assessed for PASI scores and 5 cc of blood was drawn for GGT, hs-CRP, and apo B examinations. A PASI score is a tool used to measure the severity and extent of psoriasis. PASI is an acronym for Psoriasis Area and Severity Index.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Clinical diagnosis of Psoriasis

Exclusion criteria

  • Heart Failure
  • Diabetes Mellitus
  • Kidney Disease

Treatment and study plan

Primary outcomes

  1. Gamma-Glutamyl Transferase

    Time frame: only in admission

    Gamma-Glutamyl Transferase was check in admission, reference range for adults is 5 to 40 U/L (units per liter)

  2. Apolipoprotein B

    Time frame: only in admission

    Apolipoprotein B (ApoB) is the primary apolipoprotein and is the carrier for the following lipids: chylomicrons, low-density lipoprotein ( LDL), very low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), and lipoprotein. Unit used in mg/dL

  3. High-sensitivity c-reactive protein

    Time frame: only in admission

    High-sensitivity C-reactive protein (hsCRP) is a marker of inflammation that predicts incident myocardial infarction, stroke, peripheral arterial disease, and sudden cardiac death. Unit used in mg/L

  4. PASI

    Time frame: only in admission

    A PASI (The Psoriasis Area and Severity Index) score can range from 0 to 72

Sponsors and collaborators

Lead sponsor

Universitas Sebelas Maret

Other

Registry information

Important dates

Study start
2022
Primary completion
2022
Study completion
2022
First posted
Jul 13, 2023
Registry last updated
Jul 13, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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