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Completed

NCT Number: NCT02154659

The Difference of Reflux Pattern Between the Patients Who Have Postprandial Reflux Symptoms

Gastroesophageal reflux disease is increasing worldwide. The causes of reflux symptoms are not found exactly. especially, the postprandial reflux symptoms are more common than the all day reflux symptoms. One of the causes of reflux symptoms is the relaxation of the lower sphincter of the esophagus. But, the sphincter relaxation also occur in normal people. But, there is a difference in postprandial reflux pattens between the patients and the normal people. So, in this study, we want to compare the difference of reflux pattern between the patients who have postprandial reflux symptoms and normal people though the 24hr pH monitoring.

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Key information

Conditions

Gastroesophageal Reflux Disease Deglutition Disorders Digestive System Diseases Esophageal Diseases Esophageal Motility Disorders Gastroesophageal Reflux Gastrointestinal Diseases

Age range

19 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Yonsei university College of Medicine

Seoul, South Korea

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • over 19 years old, male and female
  • normal people (control group, who has no postprandial reflux symptoms
  • patients who have postprandial reflux symptoms (postprandial reflux symptom means that within the last 6 months, postprandial reflux symptoms more than once a week for more than 1 month)

Exclusion criteria

  • patients who have nasoesophageal stricture
  • patients who have bleeding tendency
  • patients who have esophageal varix
  • patients who have cardioverter implantation
  • patients who had surgery for esophagus, stomach or duodenum
  • patients who are taking medications, gastrointestinal motility drugs

Treatment and study plan

24hr pH monitoring

Device

Primary outcomes

  1. The difference of reflux pattern at postprandial period between the patients who have postprandial reflux symptoms and the normal people

    Time frame: Within the 24 hours after the 24hr pH monitoring

    Primary Outcome - The difference of reflux pattern at postprandial period between the patients who have postprandial reflux symptoms and the normal people The postprandial reflux symptom means that the symptoms more than once for a week for more than 1 month

Secondary outcomes

  1. The difference of esophageal reflux pH between the patients who have postprandial reflux symptoms and the normal people

    Time frame: Within the 24 hours after the 24hr pH monitoring

Sponsors and collaborators

Lead sponsor

Yonsei University

Other

Registry information

Important dates

Study start
2014
Primary completion
2015
Study completion
2015
First posted
Jun 3, 2014
Registry last updated
Mar 18, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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