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Completed

NCT Number: NCT05597059

The Diagnostic Value of the First Clinical Impression of Patients Presenting to the Emergency Department (PREKEYDIA)

Finding a diagnosis for acutely ill patients places high demands on emergency medical personnel. While anamnesis and clinical examination provide initial indications and allow a tentative diagnosis, both laboratory chemistry and imaging tests are used to confirm (or exclude) the tentative diagnosis. The more precise and targeted the additional laboratory chemical or radiological diagnosis, the more quickly and economically the causal treatment of the emergency patient can be initiated.

One examination modality, which in addition to the medical history and clinical examination, could quickly provide information about the condition of the patient, their clinical picture and severity of illness, is the first clinical impression of the patient (so-called "first impression" or "end-of-bed view"). This describes the first sensory impression that the medical staff gathers from a patient. This includes visual (e.g., facial expression, gait, breathing), auditory (e.g., voice pitch, shortness of breath when speaking), and olfactory (e.g., smell of exhaled air, body odor) impressions. Clinical practice shows that a great deal of important additional information can be gathered through this first clinical impression, which, together with the history and clinical examination of the emergency patient, provides valuable clues to the underlying condition.

To date, however, only scattered data and study results exist in the medical literature on the value of the first clinical impression in the care of emergency patients. In the present prospective observational study, the study attempts to evaluate the predictive value of the first clinical impression in identifying a leading symptom and other important clinical parameters.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Kepler University Hospital

Linz, Upper Austria, 4021, Austria

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients presenting to the emergency department between 2019-09-01 and 2020-02-28.

Exclusion criteria

  • None.

Treatment and study plan

Machine Learning Prediction

Diagnostic Test

Machine Learning Prediction

Primary outcomes

  1. AUROC for Classification of Shortness of Breath

    Time frame: 2019-09-01 to 2020-02-28

    AUROC for Classification of Shortness of Breath

  2. AUROC for Classification of Extremity Pathologies

    Time frame: 2019-09-01 to 2020-02-28

    AUROC for Classification of Extremity Pathologies

  3. AUROC for Classification of Abdominal Pain

    Time frame: 2019-09-01 to 2020-02-28

    AUROC for Classification of Abdominal Pain

  4. AUROC for Classification of Urological Pathologies

    Time frame: 2019-09-01 to 2020-02-28

    AUROC for Classification of Urological Pathologies

  5. AUROC for Classification of Chest Pain

    Time frame: 2019-09-01 to 2020-02-28

    AUROC for Classification of Chest Pain

  6. AUROC for Classification of Back Pain

    Time frame: 2019-09-01 to 2020-02-28

    AUROC for Classification of Back Pain

Secondary outcomes

  1. AUROC for Classification of Hospital Admission

    Time frame: 2019-09-01 to 2020-02-28

    AUROC for Classification of Hospital Admission

  2. Confusion Matrix

    Time frame: 2019-09-01 to 2020-02-28

    Confusion Matrix Results: true positives, true negatives, false positive, false negatives and values calculated from these results.

  3. Descriptive Statistics

    Time frame: 2019-09-01 to 2020-02-28

    Descriptive Statistics (e. g. age in years)

Sponsors and collaborators

Lead sponsor

Kepler University Hospital

Other

Registry information

Official study title

The Diagnostic Value of the First Clinical Impression of Patients Presenting to the Emergency Department

Important dates

Study start
2019
Primary completion
2020
Study completion
2021
First posted
Oct 27, 2022
Registry last updated
Oct 31, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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