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Completed

NCT Number: NCT06843642

The Development of Diagnosis and Prognosis Predictive Model for Peripheral Nerve Disease

This is a retrospective observational cohort study (MRN-PND), aiming to explore the utility of contrast-enhanced MRN (ceMRN) compared to plain MRN in diagnosing peripheral nerve diseases and predicting the prognosis of patients with these conditions. Additionally, artificial intelligence (AI) methods are employed to enhance the diagnostic accuracy of MRN for peripheral nerve diseases and to precisely predict disease outcomes.

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Key information

Conditions

Peripheral Nerve Disease Nervous System Diseases Neuromuscular Diseases Peripheral Nervous System Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Union Hospital，Tongji Medical College，Huazhong University of Science and Technology

Wuhan, Hubei, 430000, China

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients who underwent MRN scanning at Wuhan Union Hospital between January 2015 and January 2025;
  • Age > 18 years;
  • Definitive clinical diagnosis (either healthy individuals or patients with a specific condition).

Exclusion criteria

：

  • Poor quality of imaging;
  • Incomplete clinical data or loss to follow-up;
  • Unclear clinical diagnosis.

Treatment and study plan

Primary outcomes

  1. Correlation analysis of MR information and diagnosis outcome

    Time frame: 0.5 year

    The indicator is the area under the curve of the predict diagnosis outcome.

Sponsors and collaborators

Lead sponsor

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Other

Collaborators

  • University Hospital Heidelberg
  • West China Hospital
  • Wuhan No.1 Hospital

Registry information

Official study title

The Development of Diagnosis and Prognosis Predictive Model for Peripheral Nerve Disease Using Big Data From Magnetic Resonance Neurography: A Multicenter Cohort Study（MRN-PND）

Important dates

Study start
2015
Primary completion
2025
Study completion
2025
First posted
Feb 25, 2025
Registry last updated
Feb 25, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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