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NCT Number: NCT07708415

The Correlation of Postoperative Polyp Recurrence and Colorectal Cancer

Postoperative endoscopic polyp recurrence correlation of colorectal cancer: a retrospective cohort open-label study

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Key information

Conditions

Colorectal Cancer Colonic Diseases Colorectal Neoplasms Digestive System Diseases Digestive System Neoplasms Gastrointestinal Diseases Gastrointestinal Neoplasms Intestinal Diseases Intestinal Neoplasms Neoplasms Neoplasms by Site Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Polyps Rectal Diseases

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

About this study

This study aims to address the gaps in existing research by focusing on the high-risk group of colorectal cancer patients post-radical surgery, systematically reviewing potential factors influencing polyp recurrence, further clarifying independent risk factors for postoperative polyp recurrence in this population, and constructing a predictive model that better aligns with the clinical needs of such patients, thereby providing more precise references for developing personalized follow-up strategies in clinical practice.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients who underwent radical surgery for colon cancer at Gansu Provincial People's Hospital from January 2015 to December 2024 and regularly completed colonoscopy follow-up after surgery were selected as the research subjects. Inclusion criteria:

Diagnosed with colon cancer through histopathological examination ; Undergoing radical R0 resection ； Complete Colonoscopy follow-up after surgery less than 12 months.

Exclusion criteria

With adenomatous polyposis , Lynch syndrome and Peutz-Jeghers syndrome； Combined inflammatory bowel disease; Polyp were present before surgery and have not been completely removed； With distant metastasis or local recurrence； Clinical data is missing and can not be analyzed.

Treatment and study plan

Endoscopic polypectomy

Procedure

Endoscopic polypectomy

Primary outcomes

  1. Adenoma recurrence after colorectal surgery

    Time frame: Postoperative；follow up till 5 years

    Postoperative colonoscopy review of colorectal cancer patients reveals adenoma recurrence

  2. Colitisafter colorectal surgery

    Time frame: Postoperative；follow up till 5 years

    Postoperative colonoscopy review of colorectal cancer patients reveals adenoma recurrence

Sponsors and collaborators

Lead sponsor

Gansu Provincial Hospital

Other

Registry information

Official study title

Postoperative Endoscopic Polyp Recurrence Correlation With Pathological Status Classification of Colorectal Cancer: a Multicenter, Retrospective Cohort Open-label Study

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jul 16, 2026
Registry last updated
Jul 16, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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