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NCT Number: NCT07698184

The Condition of the Temporomandibular Joint in Hemiplegia

Stroke is one of the leading causes of acquired disability worldwide and frequently results in medical complications and long-term sequelae. Depending on the size of the lesions and the cerebral structures affected, sensory, motor, and cognitive impairments, as well as sensory-motor deficits related to the stomatognathic system, may be present after a stroke. The stomatognathic system is a functional complex comprised of structures located in the oral and craniofacial cavities, including skeletal components, head and neck muscles, ligaments, soft tissues, the temporomandibular joint, dental arches, salivary glands, and masticatory muscles. Understanding stomatognathic system disorders is crucial for early diagnosis and implementing rehabilitation approaches to promote functional recovery. Ultrasonography is a widely available, low-cost, non-invasive, and safe medical imaging method that provides real-time observation. It offers several advantages for dentomaxillofacial imaging, including portability, dynamic and repeatable examination capabilities, patient comfort, and accessibility. It is a useful tool in identifying various pathological processes such as temporomandibular joint structures, articular disc displacement, joint effusion, and cortical erosion. There are few studies in the literature specifically on jaw disorders in stroke. The literature is quite limited in examining the jaw structure, muscles, and ligaments, as well as investigating the effect of chewing function on the clinical picture. The investigators aimed to evaluate the temporomandibular joint and chewing function in patients who developed stroke following a cerebrovascular event, and to investigate their relationship with clinical parameters.

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Key information

About this study

Stroke is one of the leading causes of acquired disability worldwide and frequently leads to medical complications and long-term sequelae. Depending on the size of the lesions and the cerebral structures affected, sensory, motor, and cognitive impairments, along with sensory-motor deficits related to the stomatognathic system, may be present after stroke . These patients may develop reduced biting force, stomatognathic disorders related to chewing quality, bruxism, joint clicking, and other temporomandibular joint disorders, which can profoundly affect their swallowing, chewing, and phonation functions, and consequently their quality of life .

The stomatognathic system is a functional complex composed of structures located in the oral and craniofacial spaces, including skeletal components, head and neck muscles, ligaments, soft tissues, the temporomandibular joint, dental arches, salivary glands, and masticatory muscles. Understanding stomatognathic system disorders is crucial for early diagnosis and implementing rehabilitation approaches to support functional recovery . Diagnosis of temporomandibular joint disorders is usually based on medical history and physical examination. During the examination, attention is paid to temporomandibular joint (TMJ) range of motion, jaw sounds, and mandibular deviations. If there are suspicious findings in the anamnesis and physical evaluation, diagnostic tools such as computed tomography and magnetic resonance imaging can be used . Ultrasonography is a widely available, low-cost, non-invasive, and safe medical imaging method that provides real-time observation. It offers several advantages for dentomaxillofacial imaging, such as portability, dynamic and repeatable examination possibilities, patient comfort, and accessibility. It is a useful tool in identifying different pathological processes such as temporomandibular joint structures, joint disc displacement, joint effusion, and cortical erosion .

There are few studies in the literature, particularly regarding jaw disorders in stroke. The literature examining the jaw structure, muscles, and ligaments, as well as investigating the effect of chewing function on the clinical picture, is quite limited. The investigators aimed to evaluate temporomandibular joint and masticatory function in patients who developed stroke following a cerebrovascular event, and to investigate its relationship with clinical parameters.

The investigators aims to improve the quality of life and rehabilitation of participants by examining all areas of rehabilitation, including sensory, motor, and cognitive aspects, as well as evaluating their jaw function, particularly swallowing, in our stroke rehabilitation clinic. It is anticipated that this will enable steps towards early diagnosis and prevention.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients who have had a stroke Ages 18-95 Those who agreed to participate in the study

Exclusion criteria

  • Patients who have previously received treatment for jaw problems
  • Those who have undergone jaw surgery
  • Those whose jaw area has been affected by trauma
  • Those who declined to participate in the study

Treatment and study plan

Primary outcomes

  1. temporomandibular joint disc thickness,

    Time frame: Baseline

    Bilateral temporomandibular joint ultrasound measurement: Participants were asked to keep their mouths closed, and then images of the right and left joint areas were taken. The joint space between the condyle and the fossa was measured.

Secondary outcomes

  1. Ultrasound measurement of temporal muscle thickness

    Time frame: Baseline

    Ultrasound images of the right and left temporal muscle regions were taken and their thickness measured while the participants were at rest with their mouths closed.

  2. Ultrasound measurement of masseter muscle thickness.

    Time frame: Baseline

    Ultrasound images of the right and left masseter muscle regions were taken and their thickness measured while the participants were at rest with their mouths closed.

  3. mouth opening measurements

    Time frame: Baseline

    Mouth opening measurements were taken with a plastic millimeter ruler.

Sponsors and collaborators

Lead sponsor

Ayşe Ukbe Baykut

Other

Registry information

Official study title

Bilateral Temporomandibular Joint Assessment and Its Relationship With Clinical Parameters in Patients Who Develop Stroke Following a Cerebrovascular Event.

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jul 13, 2026
Registry last updated
Jul 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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