Shaanxi Provincial Chang'an Compulsory Isolation Drug Rehabilitation Center
Xi'an, Shaanxi, 710062, China
NCT Number: NCT06917534
Drug addiction persists as a significant global social concern with a negative impact on social harmony and stability that cannot be ignored. After returning to society, individuals with drug addiction often suffer from impaired creative problem-solving abilities and difficulties in interpersonal cooperation. The difficulties in survival stress and the sense of helplessness triggered by these factors are important reasons that lead them to seek drugs repeatedly and even to commit criminal behaviors. Therefore, enhancing creative realistic problem-solving abilities emerges as a pivotal pathway for drug addicts to facilitate rehabilitation from drug addiction and achieve societal adaptation. The project emphasizes both individual and collaborative creative solution generation for realistic problem solving. The abnormal cognitive neural mechanisms and interpersonal neural mechanisms will be systematically explored by using multiple cognitive and neuroimaging methods, such as functional near-infrared spectroscopy (fNIRS), electroencephalography (EEG), and eye-tracking. From the cognitive-behavioral-brain level, a comprehensive neurophysiological multimodal predictive model of how drug addiction affects creative realistic problem-solving will be constructed by multi-level data fitting modeling. Building upon this research foundation, The investigators will further implement single and repeated sessions of transcranial direct current stimulation (tDCS) targeting damaged brain regions for the intervention of individual and collaborative problem-solving ability under the effect of drug addiction. The indicators of brain, cognition, and behavior will be tracked at multiple time points.
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Notify Me30 year–60 year
All sexes
Interventional
Not applicable
Xi'an, Shaanxi, 710062, China
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
The participant cohort recruited for this study consists of individuals with drug addiction specifically those addicted to drugs. During the intervention phase, this group will adhere to a strict non-pharmacological intervention protocol, meaning they will not receive any form of pharmacotherapy, neurosurgical intervention, or other neuromodulation-based cognitive interventions, including but not limited to techniques such as transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS). This design aims to ensure the internal validity of the study results and to exclude potential confounding effects of other interventions on neuroplasticity and cognitive function.
Time frame: From enrollment to the end of treatment at 1 month
Used to measure problem-solving ability individual creative problem-solving
Time frame: From enrollment to the end of treatment at 1 month
Used to measure collaborative problem-solving ability
Time frame: From enrollment to the end of treatment at 1 month
Time frame: From enrollment to the end of treatment at 1 month
Time frame: From enrollment to the end of treatment at 1 month
Time frame: From enrollment to the end of treatment at 1 month
Time frame: From enrollment to the end of treatment at 1 month
Used to measure the individual problem-solving ability
Time frame: From enrollment to the end of treatment at 1 month
Used to measure collaborative problem-solving
Time frame: From enrollment to the end of treatment at 1 month
Time frame: From enrollment to the end of treatment at 1 month
Time frame: From enrollment to the end of treatment at 1 month
Used to measure collaborative problem-solving from the perspective of social interaction.
Time frame: From enrollment to the end of treatment at 1 month
Used to measure remote associative ability.
Time frame: From enrollment to the end of treatment at 1 month
Used to measure remote association ability
Time frame: From enrollment to the end of treatment at 1 month
used to measure the divergent Association ability
Time frame: From enrollment to the end of treatment at 1 month
Used to measure cognitive flexibility.
Yifan Wang
Other
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