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NCT Number: NCT07413159

The "Check, Monitor, Control Hypertension" Study is a 24-month Randomized Trial in Houston Targeting African Americans Aged 55+. It Combines Pharmacist Counseling and CHW Support to Improve Blood Pressure Control in Hypertension Management.

The proposed study, "Check, Monitor, Control Hypertension in Older African American Adults," is a randomized clinical trial designed to improve blood pressure control among African American adults aged 55 years and older in the Greater Houston area. Hypertension disproportionately affects African Americans, contributing to higher rates of cardiovascular disease and stroke. This project aims to improve clinical and behavioral outcomes through a 24-month intervention combining pharmacist-led counseling and Community Health Worker (CHW) support.

Recruiting

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Key information

Age range

55 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

3100 Cleburne Street, Nabrit Science Building,

Houston, Texas, 77004, United States

Location status: Recruiting

Location contact

Creaque C Tyler, PharmD, BCGP

CONTACT

[email protected]

Ivy 0 Poon, Pharm.D., M.S., BCPS

CONTACT

[email protected]

713-313-4400

About this study

Hypertension (high blood pressure) is a major health concern in the United States, especially among African Americans, who experience higher rates of uncontrolled blood pressure and related complications like heart disease and stroke. This study aims to improve blood pressure control in older African American adults through a community-based approach that combines pharmacist-led counseling and Community Health Worker (CHW) support.

The study will enroll 480 African American adults aged 55 and older living in the Greater Houston area who have a history of hypertension. Participants will be randomly assigned to one of two groups: Pharmacist-only intervention - Participants receive medication therapy management and education on blood pressure monitoring and lifestyle changes; Pharmacist + CHW intervention - In addition to pharmacist counseling, participants receive personalized support from a CHW to overcome barriers like transportation and food insecurity, plus eight group health workshops each year. Both groups will receive a digital blood pressure monitor and guidance on checking blood pressure at home.

This matters because African Americans face unique challenges in managing hypertension, including contextual factors and limited access to care. By combining medical expertise with community-based support, this study hopes to empower participants to take control of their health and improve hypertension outcomes.

Timeline & Safety

Recruitment begins: January 2026 Intervention duration: 24 months Primary completion date: May 2030 The study poses minimal risk, mainly mild discomfort from blood pressure checks. Privacy will be protected using HIPAA-compliant systems, and participation is voluntary.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Individuals are eligible to the study if they are:

  • 55 years or older
  • Have at least 2 high blood pressure readings ≥ 130/80 mmHg within one month
  • Past Medical History of hypertension > 1 year
  • Taking at least 1 antihypertensive medication
  • Independent Activities of Daily Livings (ADL) and instrumental Activities of Daily Livings (iADL)
  • Have a SmartPhone
  • Live within the Greater Houston Metropolitan Areas
  • Able to speak English

Exclusion criteria

  • Unable to verbalize comprehension of study or impaired cognitive function (e.g. dementia)
  • Not able to monitor blood pressure at home
  • Plans to relocate outside Houston within the next year

Treatment and study plan

Pharmacists Only (Control Group)

Other

Medication management and disease state counseling provided by a clinical pharmacist.

Combined Intervention (Pharmacists + CHW Interventions)

Other

Participants receive CHW Individual patient assistance and group health workshops in addition to pharmacist interventions

Primary outcomes

  1. Change in Systolic Blood Pressure

    Time frame: Baseline, 6 months, 12 months, 18 months, 24 months

    Mean change in systolic blood pressure (mmHg) from baseline to 24 months, measured using standardized BP readings.

Secondary outcomes

  1. Change in Diastolic Blood Pressure

    Time frame: Baseline, 6 months, 12 months, 18 months, 24 months

    Mean change in diastolic BP from baseline to 24 months.

  2. Medication Adherence

    Time frame: Baseline, 6 months, 12 months, 18 months, 24 months

    Proportion of participants adhering to prescribed antihypertensive medications, assessed via self-report.

  3. Lifestyle Behavior Changes

    Time frame: Baseline, 6 months, 12 months

    Changes in diet, physical activity, and assessed via validated questionnaires.

Study contacts

Contact information is provided by the study sponsor or research team.

Creaque C Tyler, PharmD, BCGP

CONTACT

[email protected]

Ivy 0 Poon, Pharm.D., M.S., BCPS

CONTACT

[email protected]

713-313-4400

Sponsors and collaborators

Lead sponsor

Texas Southern University

Other

Collaborators

  • National Institute on Minority Health and Health Disparities (NIMHD)

Registry information

Official study title

Check, Monitor, Control Hypertension in Older African American Adults (#Check, Monitor, Control)

Important dates

Study start
2026
Primary completion
2028
Study completion
2030
First posted
Feb 17, 2026
Registry last updated
Apr 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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