the Change in Carotid Intima-media Thickness After Laparoscopic Sleeve Gastrectomy

The aim of this study was to compare carotid intima-media thicknesses in laparoscopic sleeve gastrectomy patients preoperatively and at the end of the first postoperative year.

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Key information

Conditions

Weight Loss Body Weight Body Weight Changes Carotis Intima-media Thickness Pathological Conditions, Signs and Symptoms Reduce the Risk of Cardiac Disease Signs and Symptoms

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Muhammed Taha Demirpolat

Istanbul, Umraniye, 34764, Turkey (Türkiye)

About this study

Obesity is not only a disease in itself, but also predisposes to many other diseases. Cardiac diseases are one of the systems that obesity predisposes to. Obesity has been found to increase the risk of cardiac disease by increasing carotid intima-media thickness in patients with obesity. Surgery is known to be the most effective treatment for obesity and laparoscopic sleeve gastrectomy is the most common bariatric surgery procedure. Laparoscopic sleeve gastrectomy may reduce the risk of cardiac disease by reducing carotid intima-media thickness in patients with obesity through effective weight loss.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

18-65 years old,
BMI > 35 kg/m2
Laparoscopic sleeve gastrectomy will be performed
patients with cardiac disease

Exclusion criteria

patients without cardiac disease
patients who performed other bariatric surgery procedures

Treatment and study plan

SURGERY

Other

All patients will be perform laparoscopic sleeve gastrectomy. Carotid intima-media thickness will be analyzed preoperatively and at the end of the first postoperative year.

Primary outcomes

carotid intima-media thickness

Time frame: From enrollment to the end of the first year after laparoscopic sleeve gastrectomy

The primary outcome of the study was to compare carotid intima-media thickness at the end of the first postoperative year after laparoscopic sleeve gastrectomy (LSG) with baseline carotid intima-media thickness in patients with obesity. The investigators will measure carotid intima-media thickness with carotid doppler ultrasound before LSG and at the end of the first year after LSG and compare the results.

Sponsors and collaborators

Lead sponsor

Umraniye Education and Research Hospital

Other Gov

Registry information

Official study title

The Effect of Laparoscopic Sleeve Gastrectomy on the Change in Carotid Intima-media Thickness in Patients With Obesity: Prospective Randomized Trial

Important dates

Study start: 2024
Primary completion: 2024
Study completion: 2025
First posted: Mar 18, 2025
Registry last updated: Mar 18, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed