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Bucharest, 011467, Romania
NCT Number: NCT00747396
The purpose of this study is to determine the long term effects of early intervention (placement into foster care) on physical, cognitive, social and brain development and psychiatric symptomatology in previously institutionalized children.
This study is active but is not currently recruiting participants.
21 year–24 year
All sexes
Interventional
Not applicable
Bucharest, 011467, Romania
The Bucharest Early Intervention Project (BEIP) was a randomized controlled trial of foster care as an intervention for children abandoned at or around the time of birth and placed in one of six institutions for young children in Bucharest, Romania (Zeanah et al., 2003). The PI (Nelson) and Co-PIs (Zeanah and Fox) conducted this study beginning in the fall of 2000 from baseline assessments and implementation of the intervention in the spring of 2001.
The BEIP began with comprehensive assessments of 136 institutionalized children and their caregiving environments prior to randomization. Half the children were randomly assigned to high-quality foster care and the other half to remain in institutional care. The average age at foster care placement was 22 months (range=6-31 months). All children were initially seen prior to randomization and again for follow-up assessments at 30 months, 42 months 54 months, 8 years, 12 year and 16 years of age. The development of children in foster care was compared to the development of children in institutions and to a group of never institutionalized children (community controls). These children, now young adults are being assessed at age 21 years.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
for assessment at age 21 years:
Exclusion criteria
for assessment at age 21 years:
A group of children living in institutions in Bucharest, Romania was randomly assigned to placement in foster care. Foster parents were recruited, consented to background checks, and trained in Romanian. Before placement, foster parents visited their children to begin developing a relationship with the child. Hired foster parents were supported and monitored by project social workers. Foster parents in the BEIP network received frequent visits from the social workers, with visits occurring weekly for several months after placement of the child, then biweekly and later monthly. Foster parents were invited to participate in a support group organized by social workers. Project social workers consulted weekly with US staff experienced in dealing with young children in foster care.
Other names: Foster Care Group
Time frame: baseline, 30 mos, 42 mos, 8 years, 12 years, 16 years, 21 years
EEG coherence
Time frame: baseline, 30 mos, 42 mos, 8 years, 12 years, 16 years, 21 years
EEG power
Time frame: baseline, 30 mos, 42 mos, 8 years, 12 years, 16 years, 21 years
EEG asymmetry
Time frame: baseline, 30 mos, 42 mos, 54 mos, 8 years, 12 years, 16 years
Disturbances of Attachment Interview
Time frame: baseline, 30 mos and 42 mos
Strange Situation Procedure
Time frame: 8 years, 12 years, 16-18 years
Wechsler Intelligence Scale for Children-IV
Time frame: 21 years
Wechsler Adult Intelligence Scale
Time frame: baseline, 30 months, 42 months
Bayley Scales of Infant Development
Time frame: baseline, 30 mos, 42 mos, 8 years, 12 years, 16 years, 21 years
weight in kilograms
Time frame: baseline, 30 mos, 42 mos, 8 years, 12 years, 16 years, 21 years
Height measured in centimeters
Time frame: baseline, 30 mos, 42 mos, 8 years, 12 years, 16 years, 21 years
Head circumference in centimeters
Time frame: 12 years, 16 years
Diagnostic Interview Schedule for Children -IV
Time frame: 54 months, 8 years
Preschool And Child Adolescent Psychological Assessment
Time frame: 21 years
Diagnostic Interview Schedule + Substance Abuse Module
Time frame: 30 mos, 42 mos and 8 years
language sample from interview
Time frame: baseline, 30 mos and 42 mos
Observational Record of Caregiving Environment
Time frame: 54 mos, 8 years and 12 years
Stranger at the Door
Time frame: baseline, 30 mos, 42 mos and 8 years
Event-related Potentials
Time frame: baseline, 30 mos, 42 mos and 8 years
Event-related Potentials
Time frame: 8 years, 16 years, 21 years
MRI
Time frame: baseline, 30 mos and 42 mos
Infant Toddler Social Emotional Assessment
Time frame: baseline, 30 mos, 42 mos, 8 years, 12 years, 16 years
Social Communication Questionnaire
Time frame: 8 years, 12 years, 16 years
Buccal Swab
Time frame: baseline, 30 mos and 42 mos
Laboratory Temperament Assessment Battery (Lab-TAB) Puppets and Peek-a-boo
Time frame: 8 years
Bruininks-Oseretsky Test-2
Time frame: 12 years, 16 years
Trier Social Stress Test
Charles Alexander Nelson III
Other
The Bucharest Early Intervention Project: Effects of Early Psychosocial Deprivation on Mental Health in Adolescence
Acronym: BEIP
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