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OpenTrials
Completed

NCT Number: NCT06166368

the Bispebjerg Study of Diurnal Variations

To evaluate the influence of time of day on the circulating concentrations of various biochemical markers in healthy men

Completed

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Key information

Conditions

Diurnal

Age range

18 year–45 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Medically healthy
  • Normal sleep-wake pattern

Exclusion criteria

  • acute or chronic medical diseases
  • had worked nightshifts the last 14 days before the study
  • transatlantic traveling the last 14 days before the study
  • had been smoking the last 14 days before the study
  • had an irregular sleep-wake pattern,
  • didn't sleep 7-8 hours pr night
  • were extreme morning- or evening types,
  • had plasma hemoglobin < 8.0 mmol/L
  • ody mass index (BMI) <18.5 kg/m2 or >24.9 kg/m2.

Treatment and study plan

Diurnal variation

Other

Venous blood samples were obtained under standardized circumstances from 24 healthy young men every third hour through 24 hours, nine time points in total.

Primary outcomes

  1. hematology parameters

    Time frame: 24 hours

    Composite measurement of hematological measurements

Secondary outcomes

  1. Plasma Levels of Glucagon

    Time frame: 24 hours

  2. Plasma levels of GLP-1

    Time frame: 24 hours

  3. Plasma levels of GIP

    Time frame: 24 hours

  4. Plasma levels of c-peptide

    Time frame: 24 hours

  5. Plasma levels of glucose

    Time frame: 24 hours

Sponsors and collaborators

Lead sponsor

Bispebjerg Hospital

Other

Collaborators

  • University of Copenhagen

Registry information

Acronym: DIURNAL

Important dates

Study start
2008
Primary completion
2009
Study completion
2009
First posted
Dec 12, 2023
Registry last updated
Dec 20, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.