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Completed

NCT Number: NCT02529917

The Benefits of Hemp Protein Supplementation During Resistance Training

Forty physically active men and women aged 18-45y will take part in an 8-week resistance training program, randomized (double blind) 1:1 into each of two groups. Twenty participants will be randomized to receive 60 g/d of hemp powder (containing approximately 40 g protein and 9 g oil) supplementation and 20 randomized to receive 60 g/d of soy supplementation (matched to the hemp for macronutrients and calories) during eight weeks of training. Each participant will complete testing before and after the intervention for assessment of body composition (lean tissue, fat, and bone mass), strength, central fatigue, markers of inflammation, and bone resorption. Over the 8-weeks of training, participants will train four-five days per week for 1-1.5 hours per session with exercises targeting all major muscle groups. The training will involve a "two day split" where different muscle groups are trained on two consecutive days (day 1 involves chest, back, and arms; day 2 legs, shoulders, and abdominals). Resistance training will provide the necessary stimulus for protein synthesis to optimize the effect of a protein-containing nutritional supplement. The hemp or soy powder will be consumed in two doses (i.e. 30 g powder containing 20 g protein per dose) immediately after exercise sessions and one hour after exercise. This dosing regimen is optimal for stimulating muscle protein synthesis and building muscle mass . On the one non-training day per week the two doses will be consumed with meals.

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Key information

Age range

18 year–45 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Saskatchewan

Saskatoon, Saskatchewan, S7N 5B2, Canada

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • At least 6 months experience with resistance training

Exclusion criteria

  • Allergies to hemp or soy
  • Consumption of other nutritional supplements in previous month
  • Answered "yes" to questions on the Physical Activity Readiness Questionnaire

Treatment and study plan

Hemp powder

Dietary Supplement

Hemp powder supplement

Soy Powder

Dietary Supplement

Soy powder supplement

Primary outcomes

  1. Change in lean tissue mass (kg)

    Time frame: 8 weeks

    Lean tissue mass measured with dual energy x-ray absrorptiometry

Secondary outcomes

  1. Change in fat mass (kg)

    Time frame: 8 weeks

    Fat mass as measured by dual energy x-ray absorptiometry

  2. Change in bone mass (grams)

    Time frame: 8 weeks

    Bone mass as measured by dual energy x-ray absorptiometry

  3. Change in elbow flexor muscle thickness (cm)

    Time frame: 8 weeks

    Muscle thickness as assessed by ultrasound

  4. Change in knee extensor muscle thickness (cm)

    Time frame: 8 weeks

    muscle thickness as measured by ultrasound

  5. Change in bench press strength (kg)

    Time frame: 8 weeks

    Bench press strength as assess on a plate-loaded machine by the 1-RM method

  6. Change in arm curl strength (kg)

    Time frame: 8 weeks

    Arm curl strength as assessed with dumbbells by the 1-RM method

  7. Change in leg press strength (kg)

    Time frame: 8 weeks

    Leg press strength as assessed on a leg-press machine by the 1-RM method

  8. Change in inflammation by interleukin-6 (mmol/l) levels

    Time frame: 8 weeks

    Interleukin-6 levels measured from saliva samples

  9. Change in inflammation by C-reactive protein (mmol/l) levels

    Time frame: 8 weeks

    C-reactive protein levels measured from saliva samples

  10. Change in bone resorption (N-telopeptides) (mmol/l)

    Time frame: 8 weeks

    N-telopeptides measured from urine samples

  11. Change in voluntary muscle activation (Nm)

    Time frame: 8 weeks

    Voluntary muscle activation as measured by the interpolated twitch technique

Sponsors and collaborators

Lead sponsor

University of Saskatchewan

Other

Registry information

Important dates

Study start
2015
Primary completion
2015
Study completion
2015
First posted
Aug 20, 2015
Registry last updated
May 5, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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