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NCT Number: NCT06896019

The Association Mechanism Between the Microbiome and the Development of Community Pneumonia Was Studied Based on the Analysis of Pulmonary Microbiota - Host Interaction Network

1. The difference of lung flora between the healthy group and the CAP group was compared, and the core flora involved in the development of CAP was identified. 2. To predict the metabolites associated with CAP. 3. Identification of genes related to immune response in CAP. 4. Construct the pulmonary microbiota - host interaction network with metabolites as the link.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Sex eligibility

All sexes

Study type

Observational

Primary location

Sun Yat-sent Memorial Hospital

Guangzhou, Guangdong, China

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • According to the CAP clinical diagnostic criteria in the Guidelines for the Diagnosis and Treatment of Community-Acquired Pneumonia in Adults in China (2016 edition), cases eligible for community-acquired pneumonia were included and screened.

Exclusion criteria

  • Alveolar lavage fluid samples without electronic bronchoscopy were excluded for mNGS etiological examination of the case.

Treatment and study plan

Community Pneumonia

Diagnostic Test

The BALF of CAP patients

Primary outcomes

  1. Community Pneumonia

    Time frame: 1 weeks

    mNGS

Sponsors and collaborators

Lead sponsor

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Other

Registry information

Important dates

Study start
2023
Primary completion
2024
Study completion
2025
First posted
Mar 26, 2025
Registry last updated
Mar 26, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.