The Association Between Residual Neuromuscular Block Risk Prediction Score and the Train-of-Four Ratio

evaluate the degree of association, and the predictive accuracy of the REPS (as a predictive tool) compared with the TOFr as a quantitative assessment tool for (rNMB) in surgical patients in the early postoperative phase. The TOFr will be measured at 0, 15, 30, 45, and 60 min after extubation.

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Muscle Relaxants Muscle Hypotonia Nervous System Diseases Neurologic Manifestations Neuromuscular Manifestations Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Assiut University Hospitals

Asyut, 71111, Egypt

Location status: Recruiting

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age group 18-65 years old
Both genders
Patients with American Society of Anesthesiologist physical status classification of 1 or 2.

Exclusion criteria

Patients who are less than 18 years old or more than 65 years old.
Patients with planned scheduled recovery in the intensive care unit or if more than 10 minutes had elapsed since tracheal extubation until NMB monitoring at the PACU.
Patients on medications that interfere with muscle activity.
Known allergy to neuromuscular blocking agents.
Pregnancy or suspected pregnancy.
Neuro-muscular diseases.
Patients refusing to participate in the study.

Treatment and study plan

residual neuromuscular block risk prediction score

Diagnostic Test

it is a clinical tool designed to estimate the likelihood of residual neuromuxcular blockade in postoperative patients

Primary outcomes

correlation between residual neuromuscular block risk prediction score and train of four

Time frame: 1 hour

Study contacts

Contact information is provided by the study sponsor or research team.

Mahmoud A Faisal, Dr

CONTACT

[email protected]

01004391577 ext. 020

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Official study title

Residual Paralysis in the Post Anesthesia Care Unit: The Association Between Residual Neuromuscular Block Risk Prediction Score and the Train-of-Four Ratio. A Prospective Single-Center Open-Label Cohort Study

Important dates

Study start: 2024
Primary completion: 2025
Study completion: 2026
First posted: Mar 27, 2025
Registry last updated: Mar 27, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Not Yet Recruiting