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OpenTrials
Completed

NCT Number: NCT01659333

The Association Between Arterial Stiffness and Assessment of Hydration State in Peritoneal Dialysis Patients

Dry weight (DW) assessment is essential for the efficient treatment of peritoneal dialysis (PD) patients but so far objective methods for DW assessment have not been established for daily clinical practice. Our aim was to evaluate hydration state in PD patients by using a body composition monitor (BCM) and calf bioimpedance (c-BI) and N-terminal prohormone of brain natriuretic peptide (NT-proBNP) levels and to compare both methods with arterial stiffness.

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Key information

Conditions

Disorders Associated With Peritoneal Dialysis

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Erciyes University Nephrology Department

Kayseri, 38039, Turkey (Türkiye)

About this study

We evaluated 60 patients using a new BCM device that implies a validated body composition model. This method allows correct quantification of extracellular fluid overload or deficiency (normal limits:-1.1 to +1.1L). Patients were assigned to normo and hypervolemic groups according to BCM results. Also, normalized calf resistivity (nRho) was calculated from resistance at 5 Khz using c-BI and the levels of NT-proBNP were measured in all study patients. The analyses of arterial stiffness were performed by using the pulse wave velocity (PWV) technique on the patients. All patients underwent conventional echocardiography and their left ventricular diastolic functions were evaluated.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Peritoneal dialysis patients
  • All participants over 18 years of age

Exclusion criteria

  • Patients with valvular heart disease
  • Patients with coronary artery disease
  • Patients with cardiomyopathy
  • Patients with ESRD who underwent hemodialysis

Treatment and study plan

Primary outcomes

  1. Terminated of patients recruiting

    Time frame: One year

Sponsors and collaborators

Lead sponsor

TC Erciyes University

Other

Registry information

Official study title

Volume Status in Peritoneal Dialysis Patients With Using Different Determining Methods.

Important dates

Study start
2011
Primary completion
2012
Study completion
2012
First posted
Aug 7, 2012
Registry last updated
Aug 7, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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