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OpenTrials
Active, Not Recruiting

NCT Number: NCT07211646

The Assessment of Human Sleep and Its Functions

The purpose of this study is to look at the effects of targeted brain stimulation when falling asleep and on sleep quality.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Insomnia Dyssomnias Mental Disorders Nervous System Diseases Sleep Disorders, Intrinsic Sleep Initiation and Maintenance Disorders Sleep Wake Disorders

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

StimScience

Berkeley, California, 94704, United States

About this study

The purpose of this study is to see the effects of targeted brain stimulation when falling asleep and on sleep quality. The study uses non-invasive Transcranial Electrical Stimulation (tES), and/or a standard electroencephalogram (EEG). We may also measure eye movements, muscle activity, and heart rhythm. We may play audio during the stimulation.

The sessions can include full overnight sleep or short nap session.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18-75 year olds

Exclusion criteria

  • Epilepsy
  • Seizure History
  • Serious head injury or brain surgery
  • Migraines
  • Metal implants in head
  • Pacemaker or implanted devices
  • Pregnancy
  • Any serious medical condition other than insomnia

Treatment and study plan

sham tES

Other

short 30s sham stimulation

Fixed tES

Other

Fixed stimulation parameters for all participants

Personalized tES

Other

Stimulation parameters personalized for each participant

Primary outcomes

  1. Sleep Efficiency Change

    Time frame: up to 6 weeks

    Sleep efficiency (time slept as a percentage time spent in bed) changes across the different interventions for each subject and aggregate that across subjects

  2. Sleep Onset Change

    Time frame: 1 day to 6 weeks

    Changes in time to fall asleep across the different interventions for each subject and aggregate that across subjects

Sponsors and collaborators

Lead sponsor

StimScience Inc.

Industry

Registry information

Acronym: SS_Sleep

Important dates

Study start
2019
Primary completion
2028
Study completion
2028
First posted
Oct 8, 2025
Registry last updated
Oct 8, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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