Ningbo first hospital
Ningbo, Zhejiang, 315000, China
NCT Number: NCT06557252
Autoimmune gastritis is currently relatively rare in China due to its insidious onset, diverse clinical manifestations involving multiple systems such as digestive, hematological, and nervous systems, and its association with other autoimmune diseases. It can also be complicated by hyperplastic gastric polyps, gastric neuroendocrine tumors, gastric adenocarcinoma, and other diseases, making it prone to clinical misdiagnosis. As a form of gastritis in the post-Helicobacter pylori era, its detection rate has been gradually increasing with the continuous improvement of endoscopic technology in China. Applying the PDCA cycle management in disease diagnosis can significantly improve the detection rate of the disease, benefiting patients. Through the PDCA management model, this study further enhanced gastroenterologists' understanding of this disease from various aspects, aiming to improve the clinical diagnosis of autoimmune gastritis.
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Observational
Ningbo, Zhejiang, 315000, China
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Endoscopy center gastroenterologists in our hospital in 2024
Exclusion criteria
Doctors who withdrew from the PDCA management midway and stopped undergoing gastroscopy.
Improve diagnostic rate
Time frame: 4months
To diagnose Autoimmune Gastritis (AIG), the following two criteria must be simultaneously met:
Endoscopic or histopathological findings, or both, that are consistent with the characteristics of autoimmune gastritis.
Positive gastric autoantibody status, including the presence of anti-parietal cell antibodies (PCA) or anti-intrinsic factor antibodies (IFA), or both.
Time frame: 4months
If only the endoscopic or histopathological findings, or both, are consistent with the characteristics of autoimmune gastritis, but the gastric autoantibody status (anti-parietal cell antibodies or anti-intrinsic factor antibodies) is not confirmed to be positive, then the case should be considered as a suspected case of Autoimmune Gastritis (AIG).
Time frame: 4months
PCA is an important indicator in the diagnosis of AIG.
Time frame: 4months
IFA is an important indicator in the diagnosis of AIG.
Contact information is provided by the study sponsor or research team.
Ningbo No. 1 Hospital
Other
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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