Catholic University of Murcia
Murcia, 30107, Spain
NCT Number: NCT03798821
Determine the efficacy of the investigational product versus placebo in reducing stress oxidative during the performance of a physical exercise of a certain intensity and duration.
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Notify Me18 year–45 year
Male
Interventional
Not applicable
Murcia, 30107, Spain
The effectiveness of a probiotic for oxidative stress after eight weeks of the product to study will be checked. the sample will be formed by cyclists that will submit to a baseline exercise and after the product is taken.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
six weeks of consumption
six weeks of consumption
six weeks of consumption
Time frame: Oxidative lipid damage will be measured by the ELISA test on two different occasions. The measurements will be made at the beginning and at six weeks of consumption of the product.
It will be measured by isoprostanes in urine 24 hours.
Time frame: Oxidative damage to DNA will be measured by the ELISA test on two different occasions. The measurements will be made at the beginning and at six weeks of consumption of the product.
Analysis of 8-oxo 2'-deoxyguanosine in 24-hour urine.
Time frame: Oxidative damage to protein will be measured by the ELISA test on two different occasions. The measurements will be made at the beginning and at six weeks of consumption of the product.
Analysis of serum carbonyl groups
Time frame: Oxidative damage to lipids will be measured by the ELISA test on two different occasions. The measurements will be made at the beginning and at six weeks of consumption of the product.
analysis of malondialdehyde in plasma
Time frame: Blood analysis will be measured by the ELISA test on two different occasions. The measurements will be made at the beginning and at six weeks of consumption of the product.
serum carbonyls. It is measured in nmol / mg proteins
Time frame: Blood analysis will be measured by the ELISA test on two different occasions. The measurements will be made at the beginning and at six weeks of consumption of the product.
Malondialdehyde in plasma
Time frame: Blood analysis will be measured by the ELISA test on two different occasions. The measurements will be made at the beginning and at six weeks of consumption of the product.
Oxidized LDL.
Time frame: Blood analysis will be measured by the ELISA test on two different occasions. The measurements will be made at the beginning and at six weeks of consumption of the product.
Antioxidant capacity.
Time frame: Blood analysis will be measured by the ELISA test on two different occasions. The measurements will be made at the beginning and at six weeks of consumption of the product.
glutathione metabolism. It is measured in nmol / mg proteins
Universidad Católica San Antonio de Murcia
Other
Nutritional Clinical Trial to Evaluate the Antioxidant Efficacy of a Product Probiotic in Research
Acronym: BIO
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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