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NCT Number: NCT07540689

The Analgesic Efficacy of M-TAPA for Laparoscopic Abdominal Surgery in Children

This investigation aims to assess the efficacy of M-TAPA in children undergoing laparoscopic abdominal surgery.

Sixty pediatric patients undergoing laparoscopic abdominal surgery under general anesthesia will be enrolled in this single-center study. Preoperatively, participants will be randomly assigned to receive either port-site local anesthetic infiltration or M-TAPA.

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Key information

Conditions

Post Operative Pain Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Signs and Symptoms

Age range

1 year–7 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Kasralainy Hospital

Cairo, Elmanial, 11562, Egypt

Location status: Recruiting

About this study

This investigation aims to assess the efficacy of M-TAPA in children undergoing laparoscopic abdominal surgery.

Sixty pediatric patients undergoing laparoscopic abdominal surgery under general anesthesia will be enrolled in this single-center study. Preoperatively, participants will be randomly assigned to a port site local anesthetic infiltration. or M-TAPA.

  • port-site local anesthetic infiltration Before the skin incision, the surgeon will inject 0.17 mL/kg of 0.25% bupivacaine (up to 2 mg/kg) via infiltration into the skin, subcutaneous tissue, and muscle fascia at the three laparoscopic ports.
  • M-TAPA. Before skin incision, Ultrasound will be used to perform bilateral M-TAPA.0.25 mL/kg of 0.25% bupivacaine will be administered at each side.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age (1-7) years.
  • Both genders.
  • American Society of Anaesthesiologists (ASA) - physical status I-II.
  • Children undergoing elective laparoscopic abdominal surgery.

Exclusion criteria

  • Parental refusal.
  • Bleeding disorders with INR > 1.5 and/or platelets < 50 000.
  • History of allergic reactions to local anesthetics.
  • Rash or signs of infection at the injection site.

Treatment and study plan

Port site infiltration

Procedure

children will receive port site LA infiltration.

M-TAPA

Procedure

Children will receive bilateral M-TAPA regional anesthesia block.

Primary outcomes

  1. FLACC pain score

    Time frame: 6 hours postoperatively.

    The FLACC (Face, Leg, Activity, Cry, Consolability) pain score ( Each category is scored on a 0-2 scale, which results in a total score of 0-10 0:comfortable, 1-3: mild discomfort, 4-6: moderate discomfort, & 7-10: severe discomfort ) (FLACC) scale pain score at 6 hours.

Study contacts

Contact information is provided by the study sponsor or research team.

Ahmed M Elhaddad, Ass.prof.

CONTACT

[email protected]

01224042847 ext. 02

Sponsors and collaborators

Lead sponsor

Kasr El Aini Hospital

Other

Registry information

Official study title

The Analgesic Efficacy of Modified Thoracoabdominal Nerve Block Through Perichondrial Approach for Laparoscopic Abdominal Surgery in Children: Randomized Controlled Trial

Acronym: M-TAPA

Important dates

Study start
2026
Primary completion
2026
Study completion
2027
First posted
Apr 20, 2026
Registry last updated
Apr 23, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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